P52145
Gene name |
arsA |
Protein name |
Arsenical pump-driving ATPase |
Names |
Arsenical resistance ATPase, Arsenite-translocating ATPase, Arsenite-transporting ATPase |
Species |
Escherichia coli |
KEGG Pathway |
ag:AAB09626 |
EC number |
7.3.2.7: Linked to the hydrolysis of a nucleoside triphosphate |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P52145
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P52145-F1 | Predicted | AlphaFoldDB |
No variants for P52145
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P52145 | |||||
No associated diseases with P52145
3 regional properties for P52145
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Anion-transporting ATPase-like domain | 10 - 291 | IPR025723-1 |
| domain | Anion-transporting ATPase-like domain | 329 - 472 | IPR025723-2 |
| domain | Anion-transporting ATPase-like domain | 482 - 581 | IPR025723-3 |
Functions
| Description | ||
|---|---|---|
| EC Number | 7.3.2.7 | Linked to the hydrolysis of a nucleoside triphosphate |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
| ATPase-coupled arsenite transmembrane transporter activity | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + arsenite(in) = ADP + phosphate + arsenite(out). |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKFLENIPSY | LFFTGKGGVG | KTSISCATAI | RLAELGKRVL | LVSTDPASNV | GQVFDQTIGN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TIQPVTAVSG | LSALEIDPQD | AAQQYRARIV | DPIIGLLPDD | VVNSISEQLS | GACTTEIAAF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DEFTGLLTDA | SLLTRFDHII | FDTAPTGHTI | RLLQLPGAWS | SFIESNPDGA | SCLGPMAGLE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KQREQYAHAV | EALSDPERTR | LVLVARLQKS | TLQEVARTHD | ELSAIGLKNQ | YLVINGVLPA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SEEKRDALAA | AIWQREQEAL | ANLPAGLSDL | PTDNLYLQPL | NMVGVSALKG | LLNEHAEITS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LPEQSPQNKP | ENMSLSVLVD | DIARSEHGLI | MLMGKGGVGK | TTMAAAIAVS | LADKGFNVHL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| TTSDPAAHLS | TTLNGSLKNL | QVSRINPHDE | TERYRQHVLE | TKGRDLDEAG | KRLLEEDLRS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| PCTEEIAVFQ | AFSRVIREAG | KRFVVMDTAP | TGHTLLLLDA | TGAYHREIAR | KMGDKGHFTT |
| 490 | 500 | 510 | 520 | 530 | 540 |
| PMMQLQDQER | TKVLLVTLPE | TTPVLEAANL | QSDLERAGIH | PWGWIINNSL | WIAQTQSPLL |
| 550 | 560 | 570 | 580 | ||
| CQRALQERPQ | IEVVKNQHAS | RIALVPVMAA | EPTGIEKLRE | LVV |