P51947

PR
Gene name
ccnh
Protein name
Cyclin-H
Names
MO15-associated protein, p36
Species
Xenopus laevis (African clawed frog)
KEGG Pathway
xla:394356
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-69 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P51947

Entry ID Method Resolution Chain Position Source
AF-P51947-F1 Predicted AlphaFoldDB

No variants for P51947

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P51947

No associated diseases with P51947

3 regional properties for P51947

Type Name Position InterPro Accession
domain Cyclin, N-terminal 75 - 158 IPR006671
domain Cyclin-like domain 62 - 152 IPR013763
domain Cyclin, C-terminal domain 2 162 - 259 IPR031658

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
transcription factor TFIIK complex A transcription factor complex that forms part of the holo TFIIH complex. In Saccharomyces/human, TFIIK contains Ccl1p/Cyclin H, Tfb3p/MAT1 and Kin28p/CDK7.

1 GO annotations of molecular function

Name Definition
cyclin-dependent protein serine/threonine kinase regulator activity Modulates the activity of a cyclin-dependent protein serine/threonine kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins.

3 GO annotations of biological process

Name Definition
cell cycle The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
DNA-templated transcription The synthesis of an RNA transcript from a DNA template.
regulation of transcription by RNA polymerase II Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MYHNSTQKKH WTFLSEDEPL RRRIQANVRY RARIRATEKP RLSEIFSLEP HEELAICKYY
70 80 90 100 110 120
EKRLLDFCNA FKPTMPKSVL GTACMYFKRF YLNNSVMEHH PRIIMLTCVF LACKVDEFNV
130 140 150 160 170 180
SSIQFVGNLG ENPLGQEKIL EQILEYELLL IQQLNFHLIV HNPYRPFEGF LIDVKTRYPM
190 200 210 220 230 240
LENPEVLRKS ADEFLNRVAL TDACLLFAPS VIALTAILST ASRAGLNMES YLTECLSLKD
250 260 270 280 290 300
NQETMSHLLD GMRRLKILVS KYEPARPEEV AALKKRLDHC HSTEVTLSVH GRKRKGYEDD
310 320
GYISKKPKTE EDEWTDEDFG DSL