Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P51819

Entry ID Method Resolution Chain Position Source
AF-P51819-F1 Predicted AlphaFoldDB

No variants for P51819

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P51819

No associated diseases with P51819

3 regional properties for P51819

Type Name Position InterPro Accession
domain Histidine kinase/HSP90-like ATPase 32 - 187 IPR003594
conserved_site Heat shock protein Hsp90, conserved site 30 - 39 IPR019805
domain Heat shock protein Hsp90, N-terminal 10 - 211 IPR020575

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
ATP-dependent protein folding chaperone Binding to a protein or a protein-containing complex to assist the protein folding process, driven by ATP hydrolysis.
unfolded protein binding Binding to an unfolded protein.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MADVQMAEAE TFAFQAEINQ LLSLIINTFY SNKEIFLREL ISNASDALDK IRFESLTDKS
70 80 90 100 110 120
KLDAQPELFI RLVPDKTNKT LSIIDSGVGM AKADLVNNLG TIARSGTKEF MEALQAGADV
130 140 150 160 170 180
SMIGQFGVGF YSAYLVAEKV IVTTKHNDDE QYIWESQAGG SFTVTRDVDG EQLGRGTKIT
190 200 210 220 230 240
LFLKEDQLEY LEERRIKDLV KKHSEFISYP IYLWTEKTTE KEISDDEDDE PKKEEEGDIE
250 260 270 280 290 300
EVDEDKEKEG KKKKKIKEVS HEWQLINKQK PIWLRKPEEI TKEEYASFYK SLTNDWEDHL
310 320 330 340 350 360
AVKHFSVEGQ LEFKAILFVP KRAPFDLFDT RKKMNNIKLY VRRVFIMDNC EELIPEYLGF
370 380 390 400 410 420
VKGVVDSDDL PLNISREMLQ QNKILKVIRK NLVKKCIEMF NEIAENKDDY NKFYEAFSKN
430 440 450 460 470 480
LKLGIHEDSQ NRAKLADLLR YYSTKSGDEL TSLKDYVTRM KEGQKDIYYI TGESKKAVEN
490 500 510 520 530 540
SPFLERLKKK GYEVLFMVDA IDEYAVGQLK EYDGKKLVSA TKEGLKLEDD DEEEKKKREE
550 560 570 580 590 600
KKKSFENLCK IIKDILGDKV EKVVVSDRIV DSPCCLVTGE YGWTANMERI MKAQALRDSS
610 620 630 640 650 660
MSSYMSSKKT MEINPDNGIM EELRKRAEAD KNDKSVKDLV LLLFETALLT SGFSLDDPNT
670 680 690 700
FGARIHRMLK LGLSIDEEEA GDDADMPALE EEAGEESKME EVD