P50977

PR
Gene name
lacG
Protein name
6-phospho-beta-galactosidase
Names
Beta-D-phosphogalactoside galactohydrolase, PGALase, P-beta-Gal, PBG
Species
Lactobacillus acidophilus
KEGG Pathway
EC number
3.2.1.85: Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

287-357 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P50977

Entry ID Method Resolution Chain Position Source
AF-P50977-F1 Predicted AlphaFoldDB

No variants for P50977

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P50977

No associated diseases with P50977

2 regional properties for P50977

Type Name Position InterPro Accession
active_site Glycoside hydrolase family 1, active site 371 - 379 IPR018120
conserved_site Glycosyl hydrolases family 1, N-terminal conserved site 9 - 23 IPR033132

Functions

Description
EC Number 3.2.1.85 Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
6-phospho-beta-galactosidase activity Catalysis of the reaction: a 6-phospho-beta-D-galactoside + H2O = 6-phospho-D-galactose + an alcohol.

1 GO annotations of biological process

Name Definition
lactose catabolic process via tagatose-6-phosphate The chemical reactions and pathways resulting in the breakdown of lactose, via the intermediate tagatose-6-phosphate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTKTLPKDFI FGGATAAYQA EGATKTDGKG RVAWDKFLEE NFWYKGDPAS DFYHNYVEDL
70 80 90 100 110 120
ELAEKFGGNV IRISIAWSRI FPNGDGEVKP NGVDFYHKLF AECDARHVEP FVTLHHFDTP
130 140 150 160 170 180
EGLHEDGDFL THEKMDDFVE YADYCFKEFP EVKYWITINE IRSVAVDQYI IGNFPPADTF
190 200 210 220 230 240
GFDKMFQTHH NQMVGHARAV KLFKHDGSKG EIGIVHALQT NYPFNESNPA DIGAAELEDL
250 260 270 280 290 300
LDNKFLVDGT FVGKYPQETM EAVKDILAAN HGGEFNIEDE FKAIDAAKDV QDFVGVDYYL
310 320 330 340 350 360
SEWMRAYDGK SEITHNGTGD KGTSKVQVKG VGEEKLPDGI ETTDWDWLIY PQGLYDKIMR
370 380 390 400 410 420
VKNDYPNIHK VYITENGIGF KDTVPDNEET DKTVHDDARI DYVKQHLEVI ADAIADGANV
430 440 450 460 470
KGYFIWSLMD VFTWTNGYTK RYGLFYVDFD TQDRYPSKTA DWFKNLAETH IIE