Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P50889
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P50889-F1 | Predicted | AlphaFoldDB |
No variants for P50889
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P50889 | |||||
No associated diseases with P50889
8 regional properties for P50889
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | S1 domain | 53 - 128 | IPR003029-1 |
| domain | S1 domain | 141 - 210 | IPR003029-2 |
| domain | S1 domain | 228 - 299 | IPR003029-3 |
| domain | S1 domain | 314 - 385 | IPR003029-4 |
| domain | RNA-binding domain, S1 | 53 - 128 | IPR022967-1 |
| domain | RNA-binding domain, S1 | 142 - 210 | IPR022967-2 |
| domain | RNA-binding domain, S1 | 229 - 299 | IPR022967-3 |
| domain | RNA-binding domain, S1 | 314 - 385 | IPR022967-4 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| ribonucleoprotein complex | A macromolecular complex that contains both RNA and protein molecules. |
| ribosome | An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| RNA binding | Binding to an RNA molecule or a portion thereof. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAHALKRILY | ATWYPDILVN | YTHSVNCRRT | LDVMSETNNE | FLAALESAAD | QIKVGDVVTG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ELLAIDNDNQ | AVVGLSTGEE | GVVPAREYSD | DRNINLADEL | KIGDTIEAVV | ISNVTSDKEG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VAYLLSKKRL | DARKAWENLS | FAEGDTVDAK | VINAVRGGLI | VDVNGVRGFV | PASMVAERFV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SDLNQFKNKD | IKAQVIEIDP | ANARLILSRK | AVAAQELAAQ | LAEVFSKLSV | GEVVEGTVAR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LTDFGAFVDL | GGVDGLVHVS | EISHDRVKNP | ADVLTKGDKV | DVKILALDTE | KGRISLSIKA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| TQRGPWDEAA | DQIAAGSVLE | GTVKRVKDFG | AFVEILPGIE | GLVHVSQISN | KRIENPSEVL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KSGDKVQVKV | LDIKPAEERI | SLSMKALEEK | PEREDRRGND | GSASRADIAA | YKQQDDSAAT |
| LGDIFGDKL |