P50756
Gene name |
cyce1 |
Protein name |
G1/S-specific cyclin-E1 |
Names |
|
Species |
Xenopus laevis (African clawed frog) |
KEGG Pathway |
xla:397840 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P50756
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P50756-F1 | Predicted | AlphaFoldDB |
No variants for P50756
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P50756 | |||||
No associated diseases with P50756
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| cell division | The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. |
| G1/S transition of mitotic cell cycle | The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated. |
| regulation of cell cycle | Any process that modulates the rate or extent of progression through the cell cycle. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPVISNPAVE | KSTKDEGTAS | CSVRSRKRKA | DVAIFLQDPD | ETLDSLEMTK | KKQYQDRGPW |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SNEMTCKSPH | KLIPTPEKEE | HEPNPTNYSH | FASLRFSPVS | VSPLPRLGWA | NQDDVWRNML |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NKDRIYLRDK | NFFQKHPQLQ | PNMRAILLDW | LMEVCEVYKL | HRETFYLAQD | FFDRFMATQK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NVIKSRLQLI | GITSLFIAAK | LEEIYPPKLH | QFSFITDGAC | TEDEITRMEL | IIMKDLGWCL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SPMTIVSWFN | VFLQVAYIRE | LQQFLRPQFP | QEIYIQIVQL | LDLCVLDICC | LEYPYGVLAA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SAMYHFSCPE | LVEKVSGFKV | TELQGCIKWL | VPFAMAIKEG | GKSKLNFFKG | VDIEDAHNIQ |
| 370 | 380 | 390 | 400 | ||
| THSGCLELME | KVYINQALLE | EQNRTSPIPT | GVLTPPQSNK | KQKSDRAD |