P50410
Gene name |
PPP2R2C |
Protein name |
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform |
Names |
PP2A subunit B isoform B55-gamma, PP2A subunit B isoform PR55-gamma, PP2A subunit B isoform R2-gamma, PP2A subunit B isoform gamma |
Species |
Oryctolagus cuniculus (Rabbit) |
KEGG Pathway |
ocu:100328617 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P50410
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P50410-F1 | Predicted | AlphaFoldDB |
No variants for P50410
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P50410 | |||||
No associated diseases with P50410
8 regional properties for P50410
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | WD40 repeat | 13 - 52 | IPR001680-1 |
| repeat | WD40 repeat | 79 - 119 | IPR001680-2 |
| repeat | WD40 repeat | 161 - 200 | IPR001680-3 |
| repeat | WD40 repeat | 211 - 251 | IPR001680-4 |
| repeat | WD40 repeat | 270 - 308 | IPR001680-5 |
| repeat | WD40 repeat | 402 - 439 | IPR001680-6 |
| conserved_site | Protein phosphatase 2A regulatory subunit PR55, conserved site | 79 - 93 | IPR018067-1 |
| conserved_site | Protein phosphatase 2A regulatory subunit PR55, conserved site | 170 - 184 | IPR018067-2 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| protein phosphatase type 2A complex | A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regulatory subunits. The catalytic and scaffolding subunits form the core enzyme, and the holoenzyme also includes the regulatory subunit. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| protein phosphatase regulator activity | Binds to and modulates the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGEDTDTRKI | NHSFLRDHSY | VTEADIISTV | EFNHTGELLA | TGDKGGRVVI | FQREPESKNA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PHSQGEYDVY | STFQSHEPEF | DYLKSLEIEE | KINKIKWLPQ | QNAAHSLLST | NDKTIKLWKI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TERDKRPEGY | NLKDEEGKLK | DLSTVTSLQV | PVLKPMDLMV | EVSPRRIFAN | GHTYHINSIS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VNSDCETYMS | ADDLRINLWH | LAVTDRSFNI | VDIKPANMED | LTEVITASEF | HPHHCNLFVY |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SSSKGSLRLC | DMRAAALCDK | HSKLFEEPED | PSNRSFFSEI | ISSVSDVKFS | HSGRYMLTRD |
| 310 | 320 | 330 | 340 | 350 | 360 |
| YLTVKVWDLN | MEARPIETYQ | VHDYLRSKLC | SLYENDCIFD | KFECAWNGSD | SVIMTGAYNN |
| 370 | 380 | 390 | 400 | 410 | 420 |
| FFRMFDRNTK | RDVTLEASRE | SSKPRAVLKP | RRVCVGGKRR | RDDISVDSLD | FTKKILHTAW |
| 430 | 440 | ||||
| HPAENIIAIA | ATNNLYIFQD | KVNSDVH |