P50273

PR
Gene name
ATP22 (TCM10, YDR350C, D9476.9)
Protein name
Mitochondrial translation factor ATP22
Names
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YDR350C
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

28-104 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P50273

Entry ID Method Resolution Chain Position Source
AF-P50273-F1 Predicted AlphaFoldDB

17 variants for P50273

Variant ID(s) Position Change Description Diseaes Association Provenance
s04-1178109 20 P>R No SGRP
s04-1178082 29 G>E No SGRP
s04-1178073 32 T>K No SGRP
s04-1178064 35 P>H No SGRP
s04-1178016 51 I>S No SGRP
s04-1177713 152 G>D No SGRP
s04-1177686 161 H>R No SGRP
s04-1177602 189 R>K No SGRP
s04-1177583 195 I>M No SGRP
s04-1177231 313 G>R No SGRP
s04-1176913 419 T>A No SGRP
s04-1176898 424 A>S No SGRP
s04-1176847 441 G>R No SGRP
s04-1176826 448 I>V No SGRP
s04-1176516 551 H>R No SGRP
s04-1176460 570 V>L No SGRP
s04-1176143 676 I>V No SGRP

No associated diseases with P50273

No regional properties for P50273

Type Name Position InterPro Accession
No domain, repeats, and functional sites for P50273

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
mitochondrial inner membrane The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.

1 GO annotations of molecular function

Name Definition
translation regulator activity Any molecular function involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome.

2 GO annotations of biological process

Name Definition
positive regulation of mitochondrial translation Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.
proton-transporting two-sector ATPase complex assembly The aggregation, arrangement and bonding together of a proton-transporting two-sector ATPase complex, a large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLKCICRVYS QPLAQMVTSP LFKHMGSAGT YTILPITNLR HLSTKNCPLK IKSNRSEPLQ
70 80 90 100 110 120
FGDFERQVPC SRKSGSSKNV QKRLYELRQL KTVLSETFGV TEYASFFESL RNALHINNCS
130 140 150 160 170 180
ENEKKKLLYD IILHQHELYP EVARKIGFYL PGEVHRWFWY HIPKSESFNH YLFLLKSDVL
190 200 210 220 230 240
LFTSNYCTRF TNRLIKGTEM ERQLATFQIF LHDETNIKFI MEKVLKLHTF DSLIALVNGL
250 260 270 280 290 300
VKAKNFRFIK VFIQALLQKL EQHCYSGKDG AKQKNLRYVK FNNTLLYYLL KSGNVELFIK
310 320 330 340 350 360
TFQEELKFIV SSGLLNHIDG NEHILNFPIH HYLNLLRISN RQEELFNVIS CLQSSPLMKY
370 380 390 400 410 420
KLFKEFLMGE LIASFQAFRD PKLVCKYLLS SYSSKASANI LNALGIWGWL YHSKSTTLTA
430 440 450 460 470 480
PTLARELKNK NNILPNTMRI GSPVTVPILT ELYRSLLSSS SVSLESGQFK NCLLDLYYKY
490 500 510 520 530 540
KSFLSEEAHK YRYWRNDTGI LNVFLNYIRF QAREPRLAYN VLLDFYSQPF AKKVVLTTTL
550 560 570 580 590 600
CPFSIVAYKN HTLTQAELSE LLQVMHKNGV PLTFKFCSAM VMHYVKMRDE KGARSWYNKI
610 620 630 640 650 660
LFGGFEIRHM ALIQIIKDQG WPFPKNFDET LLTELVENNN IKEPTDSTLF TDEDMFEEDG
670 680
KPRFNDDDVN KCTNIIRETL KSLN