Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P50175
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P50175-F1 | Predicted | AlphaFoldDB |
No variants for P50175
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P50175 | |||||
No associated diseases with P50175
No regional properties for P50175
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P50175 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| chromaffin granule lumen | The volume enclosed by the membrane of a chromaffin granule. |
| extracellular region | The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| opioid peptide activity | Naturally occurring peptide that is an opioid (any non-alkaloid having an opiate-like effect that can be reversed by naloxone or other recognized morphine antagonist). These include Leu- and Met-enkephalin, dynorphin and neoendorphin, alpha, beta, gamma and delta endorphins formed from beta-lipotropin, various pronase-resistant peptides such as beta casamorphin, and other peptides whose opiate-like action seems to be indirect. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| neuropeptide signaling pathway | A G protein-coupled receptor signaling pathway initiated by a neuropeptide binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MARFLRLCTW | LLVLGSCLLA | TVQAECSQDC | AKCSYHLVSP | GDINFLACTL | ECEGQMPSHK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IWETCKDLLQ | VSKPEFPCDS | INMFKDSNKQ | DESHLLAKKY | GGFMKRYGGF | MKKMDELYPV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EPEEEANGGE | ILAKKYGGFM | KKDADEGDTL | ANSSDLLKEL | LGTGDNRARE | GRHQESTDND |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DNMSKRYGGF | MRGLKRSPQV | EDEAKELQKR | YGGFMRRVGR | PEWWMDYQKR | YGGFLKRFAE |
| 250 | 260 | ||||
| SLPSDEEAES | YSKEVPEIEK | RYGGFMRF |