P50016
Gene name |
ths (MK1006) |
Protein name |
Thermosome subunit |
Names |
Chaperonin-like complex, CLIC |
Species |
Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938) |
KEGG Pathway |
mka:MK1006 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P50016
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P50016-F1 | Predicted | AlphaFoldDB |
No variants for P50016
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P50016 | |||||
No associated diseases with P50016
3 regional properties for P50016
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Chaperonin TCP-1, conserved site | 42 - 54 | IPR002194-1 |
| conserved_site | Chaperonin TCP-1, conserved site | 63 - 79 | IPR002194-2 |
| conserved_site | Chaperonin TCP-1, conserved site | 91 - 99 | IPR002194-3 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
| ATP-dependent protein folding chaperone | Binding to a protein or a protein-containing complex to assist the protein folding process, driven by ATP hydrolysis. |
| unfolded protein binding | Binding to an unfolded protein. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAMLAGDGRQ | VLILPEGYQR | FVGRDAQRMN | IMAARVVAET | VRTTLGPMGM | DKMLVDEMGD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VVVTNDGVTI | LEEMDIEHPA | AKMVVEVAKT | QEDEVGDGTT | TAVVLAGELL | HKAEDLLQQD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IHPTVIARGY | RMAVEKAEEI | LEEIAEEIDP | DDEETLKKIA | KTAMTGKGVE | KARDYLAELV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VKAVKQVAEE | EDGEIVIDTD | HIKLEKKEGG | GLEDTELVKG | MVIDKERVHP | GMPRRVENAK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| IALLNCPIEV | KETETDAEIR | ITDPEQLQAF | IEEEERMLSE | MVDKIAETGA | NVVFCQKGID |
| 310 | 320 | 330 | 340 | 350 | 360 |
| DLAQHYLAKK | GILAVRRVKK | SDMQKLARAT | GARIVTNIDD | LSEEDLGEAE | VVEEKKVAGD |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KMIFVEGCKD | PKAVTILIRG | GTEHVVDEAE | RAIEDAIGVV | AAALEDGKVV | AGGGAPEVEV |
| 430 | 440 | 450 | 460 | 470 | 480 |
| ARQLRDFADG | VEGREQLAVE | AFADALEIIP | RTLAENSGLD | PIDVLVQLRA | KHEDGQVTAG |
| 490 | 500 | 510 | 520 | 530 | 540 |
| IDVYDGDVKD | MLEEGVVEPL | RVKTQALASA | TEAAEMILRI | DDVIAARELS | KEEEEEEEEG |
| GSSEF |