P49985

PR
Gene name
recA
Protein name
Protein RecA
Names
Recombinase A
Species
Ruminococcus albus (strain ATCC 27210 / DSM 20455 / JCM 14654 / NCDO 2250 / 7)
KEGG Pathway
ral:Rumal_2211
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-76 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P49985

Entry ID Method Resolution Chain Position Source
AF-P49985-F1 Predicted AlphaFoldDB

No variants for P49985

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P49985

No associated diseases with P49985

4 regional properties for P49985

Type Name Position InterPro Accession
domain AAA+ ATPase domain 75 - 246 IPR003593
conserved_site DNA recombination/repair protein RecA, conserved site 231 - 239 IPR020584
domain DNA recombination and repair protein RecA, monomer-monomer interface 217 - 290 IPR020587
domain DNA recombination and repair protein RecA-like, ATP-binding domain 53 - 212 IPR020588

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP-dependent DNA damage sensor activity A molecule that recognises toxic DNA structures, and initiates a signalling response, driven by ATP hydrolysis.
damaged DNA binding Binding to damaged DNA.
single-stranded DNA binding Binding to single-stranded DNA.

3 GO annotations of biological process

Name Definition
DNA recombination Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.
DNA repair The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
SOS response An error-prone process for repairing damaged microbial DNA.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAIDKKKKEK DVKVHNITDA EEKKKALETA IAFIEKQFGK GAIMKLGDAR AMDVEAIPTG
70 80 90 100 110 120
SMMLDMALGI GGVPRGRIIE IYGPESSGKT TVALHIIAET QKMGGEVAFI DVEHALDPVY
130 140 150 160 170 180
AKNLGVDIDS MLVSQPDSGE QALEIAEALA RSGAIDCIVI DSVAAMVTKA EIDGEMGDTH
190 200 210 220 230 240
VGQLARLMSQ AMRKLTGVVS KSNTTCVFIN QVREKIGVMY GNPETTPGGR ALKFYASVRI
250 260 270 280 290 300
EVRRGEQIKD GGEVLGNRTK CKVVKNKVAP PFKECEFDIM YGKGISRVGE VLDTAVDLGI
310 320 330 340 350 360
VKKGGAWFSY EDYKLGQGRD NSKQFLLDHP DIMAEIENKI KASSAEMIAA AGQKNDKKSK
370 380 390
LEEKANAGAG ISEASEPDSS AEEDFEEFAP IDIGSLGE