P49777
Gene name |
abp1 (SPBC1105.04c) |
Protein name |
ARS-binding protein 1 |
Names |
|
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPBC1105.04c |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for P49777
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 1IUF | NMR | - | A | 1-141 | PDB |
| AF-P49777-F1 | Predicted | AlphaFoldDB |
No variants for P49777
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P49777 | |||||
No associated diseases with P49777
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| chromatin | The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome. |
| condensed chromosome, centromeric region | The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome. |
| mating-type region heterochromatin | Heterochromatic regions of the chromosome found at silenced mating-type loci. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| centromeric DNA binding | Binding to a centromere, a region of chromosome where the spindle fibers attach during mitosis and meiosis. |
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| sequence-specific DNA binding | Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| donor selection | The process that determines which donor locus a cell uses, in preference to another, in mating type switching. |
| protein localization to mating-type region heterochromatin | A process in which a protein is transported to, or maintained in, a location within a mating-type region heterochromatin. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGKIKRRAIT | EHEKRALRHY | FFQLQNRSGQ | QDLIEWFREK | FGKDISQPSV | SQILSSKYSY |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LDNTVEKPWD | VKRNRPPKYP | LLEAALFEWQ | VQQGDDATLS | GETIKRAAAI | LWHKIPEYQD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QPVPNFSNGW | LEGFRKRHIL | HAINEQPTES | VVLNNTEPPN | DPLSRVYDVT | RLTNINDIFT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| MQETGLFWKL | VPNGTPEVED | IKGITRFKAR | ITLTVCCNAS | GTERLPLWVI | GYSQSPRVFR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AANVKPEVMN | FKWRSNGKAS | MTTAIMEEWL | RWFDACMEGR | KVILLIDSYT | PHLRAVENIR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| NSGNDLRNTT | VITLPSTSAS | ISQPCSEGVI | YALKACYRKH | WVQYILEQNE | LGRNPYNTTN |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VLRAILWLVK | AWTTDISPEI | IENAFNLSGV | LGLFNESAVT | SRALDEMIHP | LRELVSEFSV |
| 430 | 440 | 450 | 460 | 470 | 480 |
| QAAMRIEDFI | SPSEENIVDS | SEDIINQIAS | QYMDDRAFET | DEEESTEFQI | TTKDAMKAIE |
| 490 | 500 | 510 | 520 | ||
| LLLNYEAQQP | DGNPAITISL | LNYQKLLEAR | GGNVNLSRLR | ST |