P48825

PR
Gene name
Protein name
Beta-glucosidase 1
Names
Beta-D-glucoside glucohydrolase, Cellobiase, Gentiobiase
Species
Aspergillus aculeatus
KEGG Pathway
EC number
3.2.1.21: Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-48 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

8 structures for P48825

Entry ID Method Resolution Chain Position Source
4IIB X-ray 180 A A/B 20-860 PDB
4IIC X-ray 190 A A/B 20-860 PDB
4IID X-ray 230 A A/B 20-860 PDB
4IIE X-ray 200 A A/B 20-860 PDB
4IIF X-ray 245 A A/B 20-860 PDB
4IIG X-ray 230 A A/B 20-860 PDB
4IIH X-ray 200 A A/B 20-860 PDB
AF-P48825-F1 Predicted AlphaFoldDB

No variants for P48825

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P48825

No associated diseases with P48825

5 regional properties for P48825

Type Name Position InterPro Accession
domain Glycoside hydrolase, family 3, N-terminal 82 - 98 IPR001764-1
domain Glycoside hydrolase, family 3, N-terminal 104 - 338 IPR001764-2
domain Glycoside hydrolase family 3 C-terminal domain 400 - 654 IPR002772
active_site Glycoside hydrolase, family 3, active site 266 - 283 IPR019800
domain Fibronectin type III-like domain 779 - 847 IPR026891

Functions

Description
EC Number 3.2.1.21 Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
beta-glucosidase activity Catalysis of the hydrolysis of terminal, non-reducing beta-D-glucose residues with release of beta-D-glucose.
scopolin beta-glucosidase activity Catalysis of the reaction: H2O + scopolin <=> beta-D-glucose + scopoletin.

1 GO annotations of biological process

Name Definition
cellulose catabolic process The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKLSWLEAAA LTAASVVSAD ELAFSPPFYP SPWANGQGEW AEAYQRAVAI VSQMTLDEKV
70 80 90 100 110 120
NLTTGTGWEL EKCVGQTGGV PRLNIGGMCL QDSPLGIRDS DYNSAFPAGV NVAATWDKNL
130 140 150 160 170 180
AYLRGQAMGQ EFSDKGIDVQ LGPAAGPLGR SPDGGRNWEG FSPDPALTGV LFAETIKGIQ
190 200 210 220 230 240
DAGVVATAKH YILNEQEHFR QVAEAAGYGF NISDTISSNV DDKTIHEMYL WPFADAVRAG
250 260 270 280 290 300
VGAIMCSYNQ INNSYGCQNS YTLNKLLKAE LGFQGFVMSD WGAHHSGVGS ALAGLDMSMP
310 320 330 340 350 360
GDITFDSATS FWGTNLTIAV LNGTVPQWRV DDMAVRIMAA YYKVGRDRLY QPPNFSSWTR
370 380 390 400 410 420
DEYGFKYFYP QEGPYEKVNH FVNVQRNHSE VIRKLGADST VLLKNNNALP LTGKERKVAI
430 440 450 460 470 480
LGEDAGSNSY GANGCSDRGC DNGTLAMAWG SGTAEFPYLV TPEQAIQAEV LKHKGSVYAI
490 500 510 520 530 540
TDNWALSQVE TLAKQASVSL VFVNSDAGEG YISVDGNEGD RNNLTLWKNG DNLIKAAANN
550 560 570 580 590 600
CNNTIVVIHS VGPVLVDEWY DHPNVTAILW AGLPGQESGN SLADVLYGRV NPGAKSPFTW
610 620 630 640 650 660
GKTREAYGDY LVRELNNGNG APQDDFSEGV FIDYRGFDKR NETPIYEFGH GLSYTTFNYS
670 680 690 700 710 720
GLHIQVLNAS SNAQVATETG AAPTFGQVGN ASDYVYPEGL TRISKFIYPW LNSTDLKASS
730 740 750 760 770 780
GDPYYGVDTA EHVPEGATDG SPQPVLPAGG GSGGNPRLYD ELIRVSVTVK NTGRVAGDAV
790 800 810 820 830 840
PQLYVSLGGP NEPKVVLRKF DRLTLKPSEE TVWTTTLTRR DLSNWDVAAQ DWVITSYPKK
850
VHVGSSSRQL PLHAALPKVQ