P48629

PR
Gene name
FAD6
Protein name
Omega-6 fatty acid desaturase, chloroplastic
Names
Species
Spinacia oleracea (Spinach)
KEGG Pathway
EC number
1.14.19.23: With oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-131 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P48629

Entry ID Method Resolution Chain Position Source
AF-P48629-F1 Predicted AlphaFoldDB

No variants for P48629

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P48629

No associated diseases with P48629

1 regional properties for P48629

Type Name Position InterPro Accession
domain Fatty acid desaturase domain 149 - 395 IPR005804

Functions

Description
EC Number 1.14.19.23 With oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
Subcellular Localization
  • Plastid, chloroplast membrane ; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
chloroplast membrane Either of the lipid bilayers that surround a chloroplast and form the chloroplast envelope.

8 GO annotations of molecular function

Name Definition
1-18:1-2-16:0-digalactosyldiacylglycerol desaturase activity Catalysis of the reaction: 1-18:1-2-16:0-digalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-16:0-digalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.
1-18:1-2-16:0-monogalactosyldiacylglycerol acyl-lipid omega-6 desaturase activity Catalysis of the reaction: 1-18:1-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-16:0-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.
1-18:1-2-16:0-phosphatidylglycerol omega-6 desaturase activity Catalysis of the reaction: 1-[(9Z)-octadec-9-enoyl]-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)(1-) + O2 + a reduced electron acceptor <=> 1-18:2-2-16:0-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor.
1-18:1-2-16:1-monogalactosyldiacylglyceroldesaturase activity Catalysis of the reaction: 1-18:1-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-16:1-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.
1-18:1-2-16:2-monogalactosyldiacylglycerol desaturase activity Catalysis of the reaction: 1-18:1-2-16:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.
1-18:1-2-16:2-monogalactosyldiacylglycerol synthase activity Catalysis of the reaction: 1-18:1-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:1-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.
1-18:1-2-trans-16:1-phosphatidylglycerol desaturase activity Catalysis of the reaction: 1-18:1-2-trans-16:1-phosphatidylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-trans-16:1-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor.
1-18:2-2-16:1-monogalactosyldiacylglycerol desaturase activity (SN2-16:2 forming) Catalysis of the reaction: 1-18:2-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:2-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.

1 GO annotations of biological process

Name Definition
unsaturated fatty acid biosynthetic process The chemical reactions and pathways resulting in the formation of an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MESAITISNH VNLAFSLSRN PSLSTKNSAG ISCIKWQRPC LRNLGHVRLN QQRKGTRRKS
70 80 90 100 110 120
TLVQAVAVPV AQPSAFPPTD NTEHLKQLAE RYGFQQIGEP LPDDVTMRDI ITSLPKQVFE
130 140 150 160 170 180
INDTKAWGTV LISVTSYALG IFMIAKAPWY LLPLAWAWTG TAITGFFVIG HDCAHKSFSK
190 200 210 220 230 240
NKLVEDIVGT LAFMPLIYPY EPWRFKHDQH HTKTNMLRED TAWLPIMKED IESSPGLRKA
250 260 270 280 290 300
LIYAYGPLRT WMSIAHWLKV HFNLKDFRQS EVKRATISLA AVFAFMVIGW PLIIYKTGIV
310 320 330 340 350 360
GWIKFWLMPW LGYHFWMSTF TIVHHTAPHI PFKSSKEWNA AQAQLSGTVH CDYPRWIEIL
370 380 390 400 410 420
CHDISVHIPH HISPKIPSYN LRAANQSLNE NWGEYLNKPK SNWRLMRTIM TTCHIYDKDG
430 440
NYVSFEKAVP EESQPISIPK RVMPDYA