| acinar cell differentiation |
The epithelial cell differentiation process in which a relatively unspecialized cell acquires specialized features of an acinar cell, a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini. |
| aorta smooth muscle tissue morphogenesis |
The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body. |
| atrial cardiac muscle tissue morphogenesis |
The process in which the anatomical structure of cardiac atrium muscle is generated and organized. |
| blood vessel endothelial cell differentiation |
The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels. |
| branching involved in pancreas morphogenesis |
The process in which the branches of the pancreas are generated and organized. |
| cell population proliferation |
The multiplication or reproduction of cells, resulting in the expansion of a cell population. |
| cerebellar granule cell differentiation |
The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar granule cell. Differentiation includes the processes involved in commitment of a neuroblast to a granule cell fate. A granule cell is a glutamatergic interneuron found in the cerebellar cortex. |
| circadian rhythm |
Any biological process in an organism that recurs with a regularity of approximately 24 hours. |
| dentate gyrus development |
The process whose specific outcome is the progression of the dentate gyrus over time, from its formation to the mature structure. The dentate gyrus is one of two interlocking gyri of the hippocampus. It contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus. |
| embryonic retina morphogenesis in camera-type eye |
The process in which the anatomical structure of the retina is generated and organized in a camera-type eye during the embryonic life stage. |
| endocardium formation |
Formation of the endocardium of the heart. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. |
| epithelial cell migration |
The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism. |
| hepatocyte cell migration |
The orderly movement of a hepatocyte during the development of the liver. Hepatocytes emerge from the hepatic epithelium, populating the septum transversum and lateral mesenchymal areas of the hepatic lobes. |
| hepatocyte differentiation |
The process in which a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver. |
| hepatocyte proliferation |
The multiplication or reproduction of hepatocytes, resulting in the expansion of a cell population. Hepatocytes form the main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. |
| inner ear development |
The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure. |
| kidney development |
The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine. |
| lens fiber cell morphogenesis |
The process in which the structures of a lens fiber cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye. |
| lens morphogenesis in camera-type eye |
The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus. |
| lens placode formation involved in camera-type eye formation |
Establishment and formation of the optic placode, paired ectodermal placodes that become invaginated to form the embryonic lens vesicles. |
| lung development |
The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax. |
| lymph vessel development |
The process whose specific outcome is the progression of a lymph vessel over time, from its formation to the mature structure. |
| lymphangiogenesis |
Lymph vessel formation when new vessels emerge from the proliferation of pre-existing vessels. |
| lymphatic endothelial cell differentiation |
The process in which a venous blood vessel endothelial cell acquires specialized features of a lymphatic vessel endothelial cell, a thin flattened cell that lines the inside surfaces of lymph vessels. |
| lymphatic endothelial cell fate commitment |
The commitment of a venous blood vessel endothelial cell to a lymphatic endothelial cell fate and its capacity to differentiate into a lymphatic endothelial cell. |
| negative regulation of bile acid biosynthetic process |
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids. |
| negative regulation of cell population proliferation |
Any process that stops, prevents or reduces the rate or extent of cell proliferation. |
| negative regulation of DNA-binding transcription factor activity |
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription. |
| negative regulation of DNA-templated transcription |
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription. |
| negative regulation of neuroblast proliferation |
Any process that stops, prevents, or reduces the frequency, rate or extent of the proliferation of neuroblasts. |
| negative regulation of transcription by RNA polymerase II |
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. |
| negative regulation of viral genome replication |
Any process that stops, prevents, or reduces the frequency, rate or extent of viral genome replication. |
| neuroblast proliferation |
The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron. |
| neuron fate determination |
The process in which a cell becomes capable of differentiating autonomously into a neuron regardless of its environment; upon determination, the cell fate cannot be reversed. |
| neuronal stem cell population maintenance |
Any process in by an organism or tissue maintains a population of neuronal stem cells. |
| positive regulation of cell cycle |
Any process that activates or increases the rate or extent of progression through the cell cycle. |
| positive regulation of cell cycle checkpoint |
Any process that activates or increases the frequency, rate or extent of cell cycle checkpoint. |
| positive regulation of cell population proliferation |
Any process that activates or increases the rate or extent of cell proliferation. |
| positive regulation of cyclin-dependent protein serine/threonine kinase activity |
Any process that activates or increases the frequency, rate or extent of CDK activity. |
| positive regulation of endothelial cell migration |
Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. |
| positive regulation of endothelial cell proliferation |
Any process that activates or increases the rate or extent of endothelial cell proliferation. |
| positive regulation of forebrain neuron differentiation |
Any process that activates or increases the frequency, rate or extent of forebrain neuron differentiation. |
| positive regulation of heart growth |
Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart. |
| positive regulation of neural precursor cell proliferation |
Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation. |
| positive regulation of sarcomere organization |
Any process that increases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs. |
| positive regulation of transcription by RNA polymerase II |
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter. |
| regulation of circadian rhythm |
Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours. |
| regulation of gene expression |
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). |
| regulation of transcription by RNA polymerase II |
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. |
| response to nutrient levels |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients. |
| skeletal muscle thin filament assembly |
The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in skeletal muscle. |
| transcription by RNA polymerase II |
The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs). |
| venous blood vessel morphogenesis |
The process in which the anatomical structures of venous blood vessels are generated and organized. Veins are blood vessels that transport blood from the body and its organs to the heart. |
| ventricular cardiac muscle tissue morphogenesis |
The process in which the anatomical structures of cardiac ventricle muscle is generated and organized. |
| ventricular cardiac myofibril assembly |
The process whose specific outcome is the progression of the ventricular cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells. |
| ventricular septum morphogenesis |
The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another. |
