P48308

PR
Gene name
L3
Protein name
Hexon protein
Names
CP-H, Protein II
Species
Murine adenovirus A serotype 1 (MAdV-1) (Murine adenovirus 1)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

18-210 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for P48308

Entry ID Method Resolution Chain Position Source

No variants for P48308

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P48308

No associated diseases with P48308

2 regional properties for P48308

Type Name Position InterPro Accession
domain Adenovirus Pll, hexon, N-terminal 8 - 591 IPR016107
domain Adenovirus Pll, hexon, C-terminal 592 - 812 IPR016108

Functions

Description
EC Number
Subcellular Localization
  • Virion
  • Host nucleus
  • Forms the capsid icosahedric shell
  • Present in 720 copies per virion, assembled in 240 trimers
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
host cell nucleus A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.
T=25 icosahedral viral capsid The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=25 symmetry. The T=25 capsid is composed of 12 pentameric and 240 hexameric capsomeres.

1 GO annotations of molecular function

Name Definition
structural molecule activity The action of a molecule that contributes to the structural integrity of a complex or its assembly within or outside a cell.

2 GO annotations of biological process

Name Definition
microtubule-dependent intracellular transport of viral material towards nucleus The directed movement of a virus, or part of a virus, towards the host cell nucleus using host microtubules.
viral entry into host cell The process that occurs after viral attachment by which a virus, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTTPSMQPQW AFMHIAGQDA SQYLSPGVVQ FAAATDTYFS LGNKFRNPTV APTHDVTTDR
70 80 90 100 110 120
SQRLTLRIVP VDREDSQYTY KTRFQLSVGD NRVLDMASTY FDIRGRLDRG PSFKPYSGTA
130 140 150 160 170 180
YNSLAPRAAP NNLMFKTGAD SKTMTIAQAN IVGSTIDQDG LKINNVALNP NAGEPAVQEG
190 200 210 220 230 240
LENWMEELQI GADKKFASRV LKADQPVLPN YGSYAYPTNI NGTQTKDGTT VDKVYMCSKG
250 260 270 280 290 300
ANVQNPDVVL YSEEVNLQAP DTHLLDGPGA DNPKDRVAFC AAPNRPNYIG FRDNFIGLMY
310 320 330 340 350 360
YNSNGNQGVL AGQASQLNAV VDLQDRNTEL SYQFLLDSLY DRSRYFSLWN QAIDSYDPRV
370 380 390 400 410 420
RIIENDGVED DITSFAFDLR GIGDLPYKQV QTHNGNQQSA NTTDTCYIGK GNMAAMEINI
430 440 450 460 470 480
PANLWLGFLY ANVAQYMPDD FKVDPSNIQM PQDKTTYAYM NQRIAPAGLI ETYVNVGGRW
490 500 510 520 530 540
SVDFMDTVNP FNHHRNEGLK YRSQILGNGR FVDFHIQVPQ KFFAIKSLLL LPGSYTYEWS
550 560 570 580 590 600
FRKDVNMVLQ SSLGNDLRAD GARLEIHSVN LYASFFPMAH NTASTLEAML RNETNDQTFL
610 620 630 640 650 660
DYLSSATMMF PIPAGQTQVP VSIPARNWAA FRGWSFTRIK QQETPNIGSP YDPYFKYSGS
670 680 690 700 710 720
IPFLDATFYL THTFQRVSIM FDSSVSWPGN DRLLTPNEFE IKRHIDAEGL CVGQSNMTKD
730 740 750 760 770 780
WFLVQMLSNY NIGYQGFYLP ENNKDRTYSF VRNFEPLARQ VVDDAAAANY RDVPLSKRFN
790 800 810 820 830 840
NSGWRSAGPP IFAREGAPYP ANWPYPLCGE AAWAAKTQRK FLVDRYMYRI PFSSNFMSMG
850 860 870 880 890 900
ALTDLGQNLL YANSAHSLEM TFNVDPMQEA TFLYILFEVF DCVRIHQPHR GIIEAVYLRS
PFSAGNATT