P48017

PR
Gene name
CHS
Protein name
Chitin synthase
Names
Chitin-UDP acetyl-glucosaminyl transferase
Species
Saprolegnia monoica
KEGG Pathway
EC number
2.4.1.16: Hexosyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-199 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P48017

Entry ID Method Resolution Chain Position Source
AF-P48017-F1 Predicted AlphaFoldDB

No variants for P48017

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P48017

No associated diseases with P48017

1 regional properties for P48017

Type Name Position InterPro Accession
domain Chitin synthase N-terminal 204 - 248 IPR013616

Functions

Description
EC Number 2.4.1.16 Hexosyltransferases
Subcellular Localization
  • Cell membrane; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
chitin synthase activity Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n) = UDP + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n+1).

2 GO annotations of biological process

Name Definition
cell wall organization A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
chitin biosynthetic process The chemical reactions and pathways resulting in the formation of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSDQLDLAAR LRALREGNAA PADPETATHT AWPAPQYHPH CRRCIHKSRS SWEGRMPRAA
70 80 90 100 110 120
PCAEAEGSYS QVPVWKDSKE TRRSYLDDEP TPQPQSLINM ANTLVQRQRR INLPAAAYSE
130 140 150 160 170 180
LPTAAQHRRG ASGRQANTAT QVLQLTCTWT LARRSSKSAE ELGTWMNTVA EEARKAALPP
190 200 210 220 230 240
QLKIARTNVP TVEQAWKGRT PPFHDADEFR LMRYTAVATK DPIQFSNDGY VLRVHQLHRR
250 260 270 280 290 300
IKVFITITMY NEEGSEILGT LTGLAKGLGY MCKEYGQDFW QEVAVAIVSD GRTKASKTCL
310 320 330 340 350 360
EYLNGLGAFD EEIMTVTSLG VDTPAGENQT FENYFPPLQV IYALKENNGG KLNSHLWFFN
370 380 390 400 410 420
AFSEQLNPKY TVLVDVGTIP AETSVFRLIR SMERNYQIGG VAGEIAVEAP NYFNPVIAAQ
430 440 450 460 470 480
HFEYKISNIM DKSLESVFGF ISVLPGAFSA YRYEAIRAVK GVGPLPEYFK SLTSTTKELG
490 500 510 520 530 540
PFQGNMYLAE DRILCFELLA RKHKQWTMHY VKDAIARTDV PETLVDLIKQ ARRWLNGSFF
550 560 570 580 590 600
AGLFAIGTLA VWSQSSHTMS RKLVFTFQFF YLALQNLLSW FLLSNLFLTF YFVLTLAFTD
610 620 630 640 650 660
SAPALLQAML TLYLAIVGGL IVFALGNKPE PRTASFYLFS CLYMGIIMML VTGISIYGLV
670 680 690 700 710 720
GKGTSAVKDP RVITGPLATV LSLKGSLSVV SSPRLGLIFL SAFVHGEFSI LLSVIQYFFM
730 740 750 760 770 780
LPTFVQFAHL SWGTKGLESG GRHGPTKTGG GKVKEVVEQQ KKLEAQRQAA AKEKEDVDNS
790 800 810 820 830 840
FRAFRSTLLA VVAHDQRHLA LRCDGLHVER VLLEGPQLVV GFFNVIVSRA ALYLLSCASL
850 860 870 880
SYSALTAVQW GPPTIPMSAT CRPTGRLITM YRTKATVGLW LPVQRA