P47716

PR
Gene name
rpoC
Protein name
DNA-directed RNA polymerase subunit beta'
Names
RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'
Species
Mycoplasma gallisepticum (strain R(low / passage 15 / clone 2)) (Mycoplasmoides gallisepticum)
KEGG Pathway
mga:MGA_1005
EC number
2.7.7.6: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-50 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P47716

Entry ID Method Resolution Chain Position Source
AF-P47716-F1 Predicted AlphaFoldDB

No variants for P47716

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P47716

No associated diseases with P47716

6 regional properties for P47716

Type Name Position InterPro Accession
domain RNA polymerase, alpha subunit 402 - 552 IPR000722
domain RNA polymerase, N-terminal 293 - 581 IPR006592
domain RNA polymerase Rpb1, domain 3 556 - 735 IPR007066
domain RNA polymerase Rpb1, domain 1 11 - 400 IPR007080
domain RNA polymerase Rpb1, domain 5 857 - 1177 IPR007081
domain RNA polymerase Rpb1, domain 4 764 - 855 IPR007083

Functions

Description
EC Number 2.7.7.6 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
DNA-directed RNA polymerase complex A protein complex that possesses DNA-directed RNA polymerase activity.

4 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-directed 5'-3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
magnesium ion binding Binding to a magnesium (Mg) ion.
zinc ion binding Binding to a zinc ion (Zn).

1 GO annotations of biological process

Name Definition
DNA-templated transcription The synthesis of an RNA transcript from a DNA template.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDKLNKKNKN KRIRGLQISI ASAEEMRSWS HGEVKKPETI NYKSLKPETD GLFDEAIFGP
70 80 90 100 110 120
VKDFECACGK YKKIKHRGRT CEKCGVEITE SIVRRERMGH IDLAVPVAHI WMTKELPSPS
130 140 150 160 170 180
KISLVLDVSY KEVEEVVYFV NYIILNPGNS KNPVFKFKEV VDLSGKGSKS ARIKLRKVLR
190 200 210 220 230 240
EIKDKHQADK HSIIYKRASD YYNKLKESHL PFSIDEVAKF IETHTGIRLG IGAEAILELL
250 260 270 280 290 300
EGVDLQKEYD LINEELNSYS KDLKANKEDQ KVKRALRRLE TIKWLKESGI KASNMILKVI
310 320 330 340 350 360
PVTPPDTRPI IQLDGARFTT SDINNFYRRI IIRNERLKKI IELRAPSVIL NNEKRMLQEV
370 380 390 400 410 420
VDALFDNASR KKPITAKDKR PLKSLTDRLK GKQGLFRQNL LGKRVDYSGR SVIVIGPELK
430 440 450 460 470 480
MYEVGIPAPM ILKLFKPFII RELIMRFNED GQEIKPIAPN IKIAEQMIAQ KSERIWDIVD
490 500 510 520 530 540
KVIKERPVLL NRAPTLHRLG IQAFEPKIVD GKAIRLHPLV TTAFNADFDG DQMAVHVPIS
550 560 570 580 590 600
KEAVAEARAI MLASWHILGP KDGKPVATPT QDMVLGNYYL TTEKRNEKGE GLIFSDFDQV
610 620 630 640 650 660
ILAYEAKQVS IHALIGLSTK CLTKKPFAKQ GIVITTVGKA IMNSIMPEEM AYLNDGDNLL
670 680 690 700 710 720
ELDESNIVFA GEDFKQKLAK RPLYKPFGKK TLSKIIEILY KNFPLQKVPQ VLDKIKEFGF
730 740 750 760 770 780
KYSTLSSTTI SVFDIPRYDN KQEYITKANE MIAKLKHMYQ KGLLTDDERY TKVIRLWADV
790 800 810 820 830 840
KDNVSRDIKE IITRPEYKEN SIVVIADSGA RGNISNFTQL FGMRGLMSKS YNYDQKIKSQ
850 860 870 880 890 900
VIRDTIEVPI KHSFIEGLTI NEYFNSSYGA RKGMTDIAMK TSKSGYMTRK LVDAAQEVII
910 920 930 940 950 960
NDSDCNTNKG IVVSTITNSL DGGVVETLSE RIVTRYTIDP IYDEKTKELL VDADTLITSE
970 980 990 1000 1010 1020
LAEKIAKANV TKALIRSPIY CQSTKGLCQK CFGNDLTTND LVQIGTAIGV IAAQSIGEPG
1030 1040 1050 1060 1070 1080
TQLTMRTFHT GGTANEGNIT QGFERLKQIF DVVSPKEWEL ATIAENEGVV ESITSDATAR
1090 1100 1110 1120 1130 1140
IIRIKTRLEA EEYRVPFDAV ISVNPKDVVY PGSKLTEGSI DIKHLLRVAG IETVRQYFLE
1150 1160 1170 1180 1190 1200
EVQKVYRLQG IEIADKYVEV TIRQLTNKLQ VIDVGDSDYF VGQTVDINKF RKEVTNMLIA
1210 1220 1230 1240 1250 1260
NKRPPVAINQ VFGLDEAPAK TGSFLSAASF QDTKKILTDA AVKNQIDYLV GLKENVILGN
1270 1280
LIPAGTGFMS SEEIIKAGEE ALEKEY