P47664

PR
Gene name
MG425
Protein name
Probable ATP-dependent RNA helicase MG425
Names
Species
Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37) (Mycoplasmoides genitalium)
KEGG Pathway
mge:MG_425
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

349-449 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P47664

Entry ID Method Resolution Chain Position Source
AF-P47664-F1 Predicted AlphaFoldDB

No variants for P47664

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P47664

No associated diseases with P47664

4 regional properties for P47664

Type Name Position InterPro Accession
domain Helicase, C-terminal 233 - 383 IPR001650
domain DEAD/DEAH box helicase domain 27 - 190 IPR011545
domain Helicase superfamily 1/2, ATP-binding domain 22 - 225 IPR014001
domain RNA helicase, DEAD-box type, Q motif 3 - 31 IPR014014

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

5 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.
RNA strand annealing activity An activity that facilitates the formation of a complementary double-stranded RNA molecule.

1 GO annotations of biological process

Name Definition
ribosomal large subunit assembly The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDSTFHELGI SQTLIETLNA LHINKPTKIQ QISIPQFLSE KNLIVHSPTG TGKTAAFAIP
70 80 90 100 110 120
IIEKLLKEDQ TAKPTLVIAP TRELVEQIKT TFSNIAKNKK LRIISLIGGV PAWKQIKKIK
130 140 150 160 170 180
TNPQIIVGTM GRIMDLLERK AIHFSDLEHL IIDEVDLMLD RGFKKQIFNL LEQINSFKQI
190 200 210 220 230 240
AVYSASYNQE AINIAKQITN NGIFIGSPEF NKDANTNNDK LIKQFVCYLF SDQKKQALYS
250 260 270 280 290 300
LIKTAQVKSI IVFCDTKKLV DDLHVFLRKN ELRTFALHGD KKQFIRERNL KIFANTKQPT
310 320 330 340 350 360
ILVTTDLIGR GIHVEAIDMV INYSACLNLE AYINRMGRTG RNNHKGTCVT FCTSQEKKVF
370 380 390 400 410 420
LKMVEKITDN RIAECKQMEI KLIPLKNKAK TKKGGISLDC VQKIYANAKP YDRNKRVPLA
430 440
SDLFKSRMRQ PEKAMQKQKI HDNDWQSNM