P47524

PR
Gene name
greA
Protein name
Transcription elongation factor GreA
Names
Transcript cleavage factor GreA
Species
Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37) (Mycoplasmoides genitalium)
KEGG Pathway
mge:MG_282
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

12-87 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P47524

Entry ID Method Resolution Chain Position Source
AF-P47524-F1 Predicted AlphaFoldDB

No variants for P47524

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P47524

No associated diseases with P47524

4 regional properties for P47524

Type Name Position InterPro Accession
domain Transcription elongation factor, GreA/GreB, C-terminal 87 - 159 IPR001437
conserved_site Transcription elongation factor, GreA/GreB, conserved site 19 - 50 IPR018151-1
conserved_site Transcription elongation factor, GreA/GreB, conserved site 124 - 140 IPR018151-2
domain Transcription elongation factor, GreA/GreB, N-terminal 6 - 75 IPR022691

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
RNA polymerase binding Binding to an RNA polymerase molecule or complex.

2 GO annotations of biological process

Name Definition
DNA-templated transcription elongation The extension of an RNA molecule after transcription initiation and promoter clearance at a DNA-dependent RNA polymerase promoter by the addition of ribonucleotides catalyzed by an RNA polymerase.
regulation of DNA-templated transcription elongation Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MELNKNYLTQ EGFKQLEKEL ENLIQVKRPE IIRLLQEARD QGDLSENADY DAAKAQQGEI
70 80 90 100 110 120
ETRIAEIQDI LANAKLISDH QAKTKVTKVS LGSTVEIYDY SSKSNEKYTI VGTLEANPEE
130 140 150 160
HKISNESPLA LAIYGRLIGD ECDVVGIEVP YRVKILKISN R