P47292
Gene name |
tsaD |
Protein name |
tRNA N6-adenosine threonylcarbamoyltransferase |
Names |
N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD |
Species |
Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37) (Mycoplasmoides genitalium) |
KEGG Pathway |
mge:MG_046 |
EC number |
2.3.1.234: Transferring groups other than amino-acyl groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P47292
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P47292-F1 | Predicted | AlphaFoldDB |
No variants for P47292
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P47292 | |||||
No associated diseases with P47292
3 regional properties for P47292
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Translation elongation factor EFTs/EF1B, dimerisation | 71 - 275 | IPR014039 |
| conserved_site | Translation elongation factor Ts, conserved site | 12 - 27 | IPR018101-1 |
| conserved_site | Translation elongation factor Ts, conserved site | 75 - 85 | IPR018101-2 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.3.1.234 | Transferring groups other than amino-acyl groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| iron ion binding | Binding to an iron (Fe) ion. |
| N(6)-L-threonylcarbamoyladenine synthase activity | Catalysis of the reaction: L-threonylcarbamoyladenylate + adenine(37) in tRNA = AMP + N(6)-L-threonylcarbamoyladenine(37) in tRNA. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| tRNA threonylcarbamoyladenosine modification | The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in tRNAs that decode ANN codons (where N is any base). |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEQPLCVLGI | ETTCDDTGLS | IVIDQKIKSN | IVISSANLHV | KTGGVVPEIA | ARCHEQNLFK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AIRDLNFEIR | DLSHIAYACN | PGLAGCLHVG | ATFARSLSFL | LDKPLLPINH | LYAHIFSCLI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DQDLNKLQLP | ALGLVISGGH | TAIYLVKSFY | ELELIAETSD | DAIGEVYDKI | GRAMGFDYPA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GSKIDSLFNK | ELVKPHYFFK | PSTKWTKFSY | SGLKSQCLNK | IKQISANKTR | IDWSELASNF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| QATIIDHYID | HVKNAIKKFA | PKMLLVGGGV | SANSYLSNRI | STLNLPFLIA | DSKYTSDNGA |
| 310 | |||||
| MIGFYASLLI | NGDKN |