P47159
Gene name |
YJR124C (J2046) |
Protein name |
Uncharacterized membrane protein YJR124C |
Names |
|
Species |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
KEGG Pathway |
sce:YJR124C |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P47159
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P47159-F1 | Predicted | AlphaFoldDB |
9 variants for P47159
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| s10-653749 | 162 | I>V | No | SGRP | |
| s10-653700 | 178 | T>N | No | SGRP | |
| s10-653691 | 181 | Q>R | No | SGRP | |
| s10-653584 | 217 | T>A | No | SGRP | |
| s10-653560 | 225 | E>K | No | SGRP | |
| s10-653509 | 242 | H>Y | No | SGRP | |
| s10-653277 | 319 | C>Y | No | SGRP | |
| s10-653074 | 387 | V>M | No | SGRP | |
| s10-653020 | 405 | I>V | No | SGRP |
No associated diseases with P47159
1 regional properties for P47159
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Major facilitator superfamily domain | 1 - 209 | IPR020846 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| fungal-type vacuole membrane | The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| transmembrane transporter activity | Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAPEIFVKFK | CASRDIKLLW | ASVFLRLLSY | GLTNQVLTLF | LNAINMTEDK | IGLFMSLTLA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GDVICSYILT | WYADSWGRRR | VLVYGCAMML | LSGLVFSFSE | NFTLLLVFAI | FGVISPSSDE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VGPFKSIEEA | MIAHLSPHNA | RPEIYAIHAL | VGTIGSALGA | IICGIFVDLL | KRTGLAATDL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QCYKLVFLLY | AFFAFCKMVI | MLLLSDATEL | DGHYEHTDCN | EETAEPLDVN | DETAPLMRQA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| THPEERSNKL | SKETVSVLMK | LLVIFMVDSL | GSGFMTSGWM | VYYYSKQFLM | GSLALGTLFF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ITQLVMASST | IPSSIIARCF | GPVRATLLVQ | IPSGIFSILI | PMAKNYLPLS | ILFLNLHFAT |
| 370 | 380 | 390 | 400 | 410 | 420 |
| TAMDVTPRQI | LLTNIIKPRD | LTKVMGVVNI | GKTFARCVGP | IFTGILANNN | YLWLCYIISG |
| 430 | 440 | ||||
| SLVITADLIL | ACMFLGVDAK | IKKQMNRH |