P47158

PR
Gene name
IBA57 (CAF17, YJR122W, J2043)
Protein name
Putative transferase CAF17, mitochondrial
Names
57 kDa iron-sulfur cluster assembly factor for biotin synthase- and aconitase-like mitochondrial proteins, CCR4-associated factor 17
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YJR122W
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

363-457 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P47158

Entry ID Method Resolution Chain Position Source
AF-P47158-F1 Predicted AlphaFoldDB

16 variants for P47158

Variant ID(s) Position Change Description Diseaes Association Provenance
s10-649796 9 I>M No SGRP
s10-650049 94 T>A No SGRP
s10-650071 101 V>A No SGRP
s10-650161 131 S>L No SGRP
s10-650259 164 S>P No SGRP
s10-650293 175 G>E No SGRP
s10-650344 192 N>S No SGRP
s10-650400 211 V>I No SGRP
s10-650578 270 S>L No SGRP
s10-650619 284 V>I No SGRP
s10-650701 311 K>R No SGRP
s10-650729 320 R>S No SGRP
s10-650986 406 E>A No SGRP
s10-651003 412 N>H No SGRP
s10-651016 416 L>P No SGRP
s10-651099 444 Y>N No SGRP

No associated diseases with P47158

1 regional properties for P47158

Type Name Position InterPro Accession
conserved_site YgfZ/GcvT conserved site 318 - 382 IPR017703

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion matrix
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
mitochondrial matrix The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

1 GO annotations of molecular function

Name Definition
transferase activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.

3 GO annotations of biological process

Name Definition
iron-sulfur cluster assembly The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.
protein maturation by [2Fe-2S] cluster transfer The transfer of an assembled
protein maturation by [4Fe-4S] cluster transfer The transfer of an assembled 4Fe-4S] cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MFISRRCRIK GFTLKNLLWF RSSSTRFVST ESPDASAITK PDGIFNYSLL ENRTYIRIRG
70 80 90 100 110 120
PDTVKFLNGL VTSKLLPHFI KKNLTTVEEN EVPTEEGTTK VDPIIPVPEF DARLGNWGLY
130 140 150 160 170 180
NEKGIQGPYI SRFGLYSAFL NGKGKLITDT IIYPTPVTVS EQISNYPEYL LELHGNVVDK
190 200 210 220 230 240
ILHVLQTHKL ANKIKFEKID HSSLKTWDVE VQFPNLPKDI ENPWFDNLLD PMALPKNSID
250 260 270 280 290 300
ANNFAVNVLN SLFNSDPRIL GIYVERRTES MSRHYSTFPQ SFRVVTSEQV DDLSKLFNFN
310 320 330 340 350 360
VFDFPFQVNK KASVQVREIR FQKGLIDSTE DYISETLLPL ELNFDFFPNT ISTNKGCYVG
370 380 390 400 410 420
QELTARTYAT GILRKRLVPV KLDNYQLLDT DPERKYAEFH IDNVVEKSLA ENEPTLNPFT
430 440 450 460 470 480
NKPPERTKRK QRPAGLLISN EGLYGVALLR TEHFSAAFSS DEPVEFYITT TKGENIKITP
490
QKPFWFSDWK NNNGPHK