P47076
Gene name |
RPC17 (YJL011C, J1349) |
Protein name |
DNA-directed RNA polymerase III subunit RPC9 |
Names |
RNA polymerase III subunit C9, RNA polymerase III subunit C17 |
Species |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
KEGG Pathway |
sce:YJL011C |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
27 structures for P47076
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 2CKZ | X-ray | 320 A | A/C | 1-161 | PDB |
| 5FJ8 | EM | 390 A | D | 1-161 | PDB |
| 5FJ9 | EM | 460 A | D | 1-161 | PDB |
| 5FJA | EM | 465 A | D | 1-161 | PDB |
| 6CNB | EM | 410 A | D | 1-161 | PDB |
| 6CNC | EM | 410 A | D | 1-161 | PDB |
| 6CND | EM | 480 A | D | 1-161 | PDB |
| 6CNF | EM | 450 A | D | 1-161 | PDB |
| 6EU0 | EM | 400 A | D | 1-161 | PDB |
| 6EU1 | EM | 340 A | D | 1-161 | PDB |
| 6EU2 | EM | 340 A | D | 1-161 | PDB |
| 6EU3 | EM | 330 A | D | 1-161 | PDB |
| 6F40 | EM | 370 A | D | 1-161 | PDB |
| 6F41 | EM | 430 A | D | 1-161 | PDB |
| 6F42 | EM | 550 A | D | 1-161 | PDB |
| 6F44 | EM | 420 A | D | 1-161 | PDB |
| 6TUT | EM | 325 A | D | 1-161 | PDB |
| 7Z0H | EM | 260 A | D | 1-161 | PDB |
| 7Z1L | EM | 280 A | D | 1-161 | PDB |
| 7Z1M | EM | 340 A | D | 1-161 | PDB |
| 7Z1N | EM | 390 A | D | 1-161 | PDB |
| 7Z1O | EM | 270 A | D | 1-161 | PDB |
| 7Z2Z | EM | 307 A | D | 1-161 | PDB |
| 7Z30 | EM | 290 A | D | 1-161 | PDB |
| 7Z31 | EM | 276 A | D | 1-161 | PDB |
| 8BWS | EM | 320 A | D | 1-161 | PDB |
| AF-P47076-F1 | Predicted | AlphaFoldDB |
2 variants for P47076
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| s10-414538 | 76 | E>G | No | SGRP | |
| s10-414536 | 77 | D>Y | No | SGRP |
No associated diseases with P47076
No regional properties for P47076
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P47076 | |||
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| nucleoplasm | That part of the nuclear content other than the chromosomes or the nucleolus. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| RNA polymerase III complex | RNA polymerase III, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces 5S rRNA, tRNAs and some of the small nuclear RNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase I and others of which are also found in RNA polymerases I and II. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| nucleotide binding | Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| termination of RNA polymerase III transcription | A transcription termination process that completes the production of a primary RNA polymerase II transcript. RNA polymerase III has an intrinsic ability to terminate transcription upon incorporation of at least 4 contiguous U residues. |
| transcription by RNA polymerase III | The synthesis of RNA from a DNA template by RNA polymerase III, originating at an RNAP III promoter. |
| transcription initiation at RNA polymerase III promoter | A transcription initiation process that takes place at a RNA polymerase III gene promoter. Transfer RNAs (tRNA) genes, as well as some other non-coding RNAs, are transcribed by RNA polymerase III. |
| tRNA transcription by RNA polymerase III | The synthesis of transfer RNA (tRNA) from a DNA template by RNA polymerase III (Pol III), originating at a Pol III promoter. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKVLEERNAF | LSDYEVLKFL | TDLEKKHLWD | QKSLAALKKS | RSKGKQNRPY | NHPELQGITR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NVVNYLSINK | NFINQEDEGE | ERESSGAKDA | EKSGISKMSD | ESFAELMTKL | NSFKLFKAEK |
| 130 | 140 | 150 | 160 | ||
| LQIVNQLPAN | MVHLYSIVEE | CDARFDEKTI | EEMLEIISGY | A |