AiPD: Autoinhibited Protein Database

Gene name	SSY5 (APF8, YJL156C, J0570)
Protein name	SPS-sensor serine protease component SSY5
Names	Endoprotease SSY5
Species	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway	sce:YJL156C
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

1-192 (Predicted disordered autoinhibitory region) PR

1-192 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-P47002-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
s10-128922	10	K>E	No	SGRP
s10-128888	21	P>H	No	SGRP
s10-128818	44	D>E	No	SGRP
s10-128819	44	D>G	No	SGRP
s10-128807	48	H>R	No	SGRP
s10-128802	50	T>A	No	SGRP
s10-128723	76	R>K	No	SGRP
s10-128649	101	H>Y	No	SGRP
s10-128643	103	G>R	No	SGRP
s10-128610	114	K>E	No	SGRP
s10-128570	127	S>N	No	SGRP
s10-128531 s10-128532	140	T>S	No	SGRP
s10-128486	155	E>G	No	SGRP
s10-128262	230	S>P	No	SGRP
s10-128120	277	D>G	No	SGRP
s10-127875	359	I>V	No	SGRP
s10-127773	393	A>P	No	SGRP
s10-127752	400	A>S	No	SGRP
s10-127731	407	S>P	No	SGRP
s10-127605	449	K>E	No	SGRP
s10-127600	450	K>N	No	SGRP
s10-126897	685	A>S	No	SGRP

Type	Name	Position	InterPro Accession
No domain, repeats, and functional sites for P47002

		Description
EC Number
Subcellular Localization	Cell membrane ; Peripheral membrane protein ; Cytoplasmic side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
extrinsic component of plasma membrane	The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.

Name	Definition
serine-type endopeptidase activity	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

Name	Definition
protein autoprocessing	Processing which a protein carries out itself. This involves actions such as the autolytic removal of residues to generate the mature form of the protein.
protein processing	Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.
response to amino acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
No homologous proteins