P46800
Gene name |
gpbB (DDB_G0275045) |
Protein name |
Guanine nucleotide-binding protein subunit beta-like protein |
Names |
|
Species |
Dictyostelium discoideum (Slime mold) |
KEGG Pathway |
ddi:DDB_G0275045 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P46800
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P46800-F1 | Predicted | AlphaFoldDB |
No variants for P46800
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P46800 | |||||
No associated diseases with P46800
10 regional properties for P46800
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | WD40 repeat | 10 - 59 | IPR001680-1 |
| repeat | WD40 repeat | 59 - 140 | IPR001680-2 |
| repeat | WD40 repeat | 142 - 275 | IPR001680-3 |
| repeat | WD40 repeat | 286 - 325 | IPR001680-4 |
| conserved_site | WD40 repeat, conserved site | 85 - 99 | IPR019775-1 |
| conserved_site | WD40 repeat, conserved site | 171 - 185 | IPR019775-2 |
| conserved_site | WD40 repeat, conserved site | 213 - 227 | IPR019775-3 |
| repeat | G-protein beta WD-40 repeat | 85 - 99 | IPR020472-1 |
| repeat | G-protein beta WD-40 repeat | 127 - 141 | IPR020472-2 |
| repeat | G-protein beta WD-40 repeat | 171 - 185 | IPR020472-3 |
8 GO annotations of cellular component
| Name | Definition |
|---|---|
| cell leading edge | The area of a motile cell closest to the direction of movement. |
| cell periphery | The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures. |
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| extracellular matrix | A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| phagocytic vesicle | A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis. |
| small ribosomal subunit | The smaller of the two subunits of a ribosome. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| identical protein binding | Binding to an identical protein or proteins. |
| phosphatidylinositol binding | Binding to an inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives. |
| protein kinase C binding | Binding to protein kinase C. |
| ribosome binding | Binding to a ribosome. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| positive regulation of protein phosphorylation | Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein. |
| rescue of stalled ribosome | A process of translational elongation that takes place when a ribosome has stalled during translation, and results in freeing the ribosome from the stalled translation complex. |
| sorocarp development | The process whose specific outcome is the progression of the sorocarp over time, from its formation to the mature structure. The process begins with the aggregation of individual cells and ends with the mature sorocarp. The sorocarp is a structure containing a spore-bearing sorus that sits on top of a stalk. An example of this process is found in Dictyostelium discoideum. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEQQKAPQVT | YLEVGSLVGH | NGFVTSIAVS | PENPDTIISS | SRDKTVMVWQ | LTPTDATSPG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KAHRSLKGHS | HFVQDVVISH | DGQFALSGSW | DNTLRLWDIT | KGVSTRLFKG | HTQDVMSVAF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SSDNRQIISG | SRDATIKVWN | TLGECKFTLE | GPEAHQDWVS | CIRFSPNTPT | IVSGSWDNKV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KIWDIKSFKC | NHTLTDHTGY | VNTVTISPDG | SLCASGGKDT | FACLWELSSG | KPLYKLEARN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TINALAFSPN | KYWLSAATDD | KIIIWDLLTK | QVLAEIVPEV | KEQAFDSKKK | KESKPKAPAC |
| 310 | 320 | ||||
| LSLAWSADGS | VLYAGYNDGL | IRVYKSSSQ |