Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P46512

Entry ID Method Resolution Chain Position Source
AF-P46512-F1 Predicted AlphaFoldDB

No variants for P46512

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P46512

No associated diseases with P46512

3 regional properties for P46512

Type Name Position InterPro Accession
domain Lactate/malate dehydrogenase, N-terminal 23 - 161 IPR001236
active_site L-lactate dehydrogenase, active site 191 - 197 IPR018177
domain Lactate/malate dehydrogenase, C-terminal 165 - 330 IPR022383

Functions

Description
EC Number 4.2.1.1 Hydro-lyases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
carbonate dehydratase activity Catalysis of the reaction: H2CO3 = CO2 + H2O.
zinc ion binding Binding to a zinc ion (Zn).

1 GO annotations of biological process

Name Definition
carbon utilization A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary carbon sources and then activates genes to scavenge the last traces of the primary carbon source and to transport and metabolize alternative carbon sources such as carbon dioxide or carbonic acid. The utilization process begins when the cell or organism detects carbon levels, includes the activation of genes whose products detect, transport or metabolize carbon-containing substances, and ends when carbon is incorporated into the cell or organism's metabolism.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSTASAFAIN APSFVNASSL KKSSTSSARS GVLSARFTCN SSSSSSSATP PSLIRNEPVF
70 80 90 100 110 120
AAPAPIITPN WTEDGNESYE EAIDALKKML IEKGELEPVA AARIDQITAQ AAAPDTKAPF
130 140 150 160 170 180
DPVERIKSGF VKFKTEKFVT NPALYDELAK GQSPKFMVFA CSDSRVCPSH VLDFQPGEAF
190 200 210 220 230 240
VVRNVANMVP PFDKTKYSGV GAAVEYAVLH LKVQEIFVIG HSRCGGIKGL MTFPDEGPHS
250 260 270 280 290 300
TDFIEDWVKV CLPAKSKVVA EHNGTHLDDQ CVQCEKEAVN VSLGNLLTYP FVRDGLRNNT
310 320
LALKGGHYDF VNGTFELWAL DFGLSSPTSV