Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P46272
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P46272-F1 | Predicted | AlphaFoldDB |
No variants for P46272
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P46272 | |||||
No associated diseases with P46272
6 regional properties for P46272
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | RNA-dependent RNA polymerase, alsuviricetes | 1470 - 1785 | IPR001788 |
| domain | Alphavirus-like methyltransferase (MT) domain | 43 - 336 | IPR002588 |
| domain | Oxoglutarate/iron-dependent dioxygenase | 747 - 835 | IPR005123 |
| domain | RNA-directed RNA polymerase, catalytic domain | 1633 - 1740 | IPR007094 |
| domain | RNA-directed RNA polymerase, apple chlorotic leaf spot virus | 843 - 934 | IPR008744 |
| domain | (+) RNA virus helicase core domain | 1032 - 1336 | IPR027351 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA-templated transcription initiation | The initial step of transcription, consisting of the assembly of the RNA polymerase preinitiation complex (PIC) at a gene promoter, as well as the formation of the first few bonds of the RNA transcript. Transcription initiation includes abortive initiation events, which occur when the first few nucleotides are repeatedly synthesized and then released, and ends when promoter clearance takes place. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTGDVDMSLH | PSGIIPELQN | VVSTVNLGCT | LELKEIAMQA | RNAEYNPKRF | AAVIMRIRDP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KTTALIFGSG | KMVCTGAKSE | QDSRTAARKY | AKIVQKLGFP | AKFTEFKIQN | IVGSCDVKFP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IRMEPLAYQH | QQFCSYEPEL | FPGLIYRMLQ | PKIVLLIFVS | GKVVLTGAKE | RTEIYRAFEQ |
| 190 | |||||
| IYPVLTQFRK | R |