P46223

PR
Gene name
RpL7A (SURF-3, CG3314)
Protein name
60S ribosomal protein L7a
Names
Species
Drosophila melanogaster (Fruit fly)
KEGG Pathway
dme:Dmel_CG3314
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-58 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

5 structures for P46223

Entry ID Method Resolution Chain Position Source
4V6W EM 600 A CG 1-271 PDB
6XU6 EM 350 A CG 31-271 PDB
6XU7 EM 490 A CG 31-271 PDB
6XU8 EM 300 A CG 31-271 PDB
AF-P46223-F1 Predicted AlphaFoldDB

No variants for P46223

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P46223

No associated diseases with P46223

2 regional properties for P46223

Type Name Position InterPro Accession
conserved_site Ribosomal protein L7Ae conserved site 179 - 196 IPR004037
domain Ribosomal protein L7Ae/L30e/S12e/Gadd45 135 - 219 IPR004038

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytosolic large ribosomal subunit The large subunit of a ribosome located in the cytosol.
cytosolic ribosome A ribosome located in the cytosol.

2 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

2 GO annotations of biological process

Name Definition
cytoplasmic translation The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.
maturation of LSU-rRNA Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P35685 RPL7A-1 60S ribosomal protein L7a-1 Oryza sativa subsp japonica (Rice) PR
10 20 30 40 50 60
MVVKKPRPKK KPVTKKVAPA PLAVKKPVVK KVVNQLFEKR PKNFGIGQNV QPKRDLSRFV
70 80 90 100 110 120
RWPKYIRVQR QKAVLQKRLK VPPPIHQFSQ TLDKTTAVKL FKLLEKYRPE SPLAKKLRLK
130 140 150 160 170 180
KIAEAKAKGK DVEPKKKPSY VSAGTNTVTK LIEQKKAQLV VIAHDVDPLE LVLFLPALCR
190 200 210 220 230 240
KMGVPYCIVK GKARLGRLVR RKTCTTLALT TVDNNDKANF GKVLEAVKTN FNERHEEIRR
250 260 270
HWGGGILGSK SLARISKLER AKARELAQKQ G