P46105
Gene name |
actII-2 (SCO5083, SCBAC28G1.09) |
Protein name |
Probable actinorhodin transporter |
Names |
|
Species |
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) |
KEGG Pathway |
sco:SCO5083 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P46105
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P46105-F1 | Predicted | AlphaFoldDB |
No variants for P46105
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P46105 | |||||
No associated diseases with P46105
1 regional properties for P46105
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Major facilitator superfamily domain | 43 - 573 | IPR020846 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| transmembrane transporter activity | Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| response to antibiotic | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSSVEADEPD | RATAPPSALL | PEDGPGPDGT | AAGPPPYARR | WAALGVILGA | EIMDLLDGTV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| MNVAAPAVRA | DLGGSLSVIQ | WITVGYTLAF | AVLLVVGGRL | GDIYGRKRMF | VVGAVGFTAA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SVLCSVAAGP | EMLTAARFLQ | GGLGALMIPQ | GLGLIKQMFP | PKETAAAFGA | FGPAIGLGAV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LGPIVAGFLV | DADLFGTGWR | SVFLINLPIG | VAVIVGAVLL | LPEGKAPVRP | KFDVVGMALV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TSGLTLLIFP | LVQGRERGWP | AWAFVLMLAG | AAVLVGFVAH | ELRQERRGGA | TLIELSLLRR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SRYAAGLAVA | LVFFTGVSGM | SLLLALHLQI | GLGFSPTRAA | LTMTPWSVFL | VVGAILTGAV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LGSKFGRKAL | HGGLVVLALG | VLIMLLTIGD | QAGGLTSWEL | VPGIAVAGLG | MGIMIGLLFD |
| 430 | 440 | 450 | 460 | 470 | 480 |
| IALADVDKQE | AGTASGVLTA | VQQLGFTVGV | AVLGTLFFGL | LGSQATASVD | DGASRARTEL |
| 490 | 500 | 510 | 520 | 530 | 540 |
| AAAGASTTEQ | DRLLADLRVC | LRESASQQDS | ERTPDSCRNL | QQARPAVAEA | TARAWRTAHT |
| 550 | 560 | 570 | |||
| ENFSTAMVRT | LWVVIALLAV | SFALAFRLPP | KPREEEGF |