P45860
Gene name |
ywiE (BSU37240) |
Protein name |
Probable cardiolipin synthase YwiE |
Names |
CL synthase 1 |
Species |
Bacillus subtilis (strain 168) |
KEGG Pathway |
bsu:BSU37240 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P45860
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P45860-F1 | Predicted | AlphaFoldDB |
No variants for P45860
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P45860 | |||||
No associated diseases with P45860
5 regional properties for P45860
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Phospholipase D/Transphosphatidylase | 237 - 264 | IPR001736-1 |
| domain | Phospholipase D/Transphosphatidylase | 413 - 440 | IPR001736-2 |
| domain | Phospholipase D-like domain | 155 - 297 | IPR025202-1 |
| domain | Phospholipase D-like domain | 342 - 467 | IPR025202-2 |
| domain | Cardiolipin synthase N-terminal | 42 - 82 | IPR027379 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| cardiolipin synthase activity | Catalysis of the reaction: phosphatidylglycerol + phosphatidylglycerol = diphosphatidylglycerol (cardiolipin) + glycerol. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| cardiolipin biosynthetic process | The chemical reactions and pathways resulting in the formation of cardiolipin, 1,3-bis(3-phosphatidyl)glycerol. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLKRRLEFFF | LYMMLIGAYV | IWFFPVSRLE | FYGGLLCYIS | IILFSIYSLI | LENRTSQHTL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LWIHILVFFP | IVGYVFYLFS | GQLYVKGKLF | KTKRMYNREK | LRKLFDKEET | PEVTGLKDNQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ERFFTYSIRA | AHMNINTKSN | IKVLKNGEET | FPDIFKAMRK | AESYIHIEYY | MFKSDMLGRG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| MMDIMMEKAR | QGVEVRFLYD | AAGSMKLARR | DIMRMKQAGV | DIVPFSPLKY | GFFNQKLNFR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| NHRKIVIIDG | KTGFVGGLNV | GKEYISRDPY | IGFWRDTHLR | LEGEIVQTLH | AIFMLDWEYV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SNEVLIDQEE | YNTPVPVEGG | GIYQIVATGP | DMKESMSDLY | YEMISSAQKS | IWIATPYFVP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| NESIRTALKA | AATKGVEVRV | MVPEKNDSFL | TQYASRSYFP | ELLLEGIEVY | SYQKGFMHQK |
| 430 | 440 | 450 | 460 | 470 | 480 |
| VMIIDGDLAS | VGTANMDMRS | FQLNFEVNVF | FTDAEAIRTL | EAHFEEDMQE | SEKLSPVGFY |
| 490 | |||||
| KRGVADRTKE | SFARLFSGVL |