Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P45739

Entry ID Method Resolution Chain Position Source
AF-P45739-F1 Predicted AlphaFoldDB

No variants for P45739

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P45739

No associated diseases with P45739

1 regional properties for P45739

Type Name Position InterPro Accession
conserved_site Eukaryotic translation initiation factor 4E (eIF-4E), conserved site 90 - 113 IPR019770

Functions

Description
EC Number 1.11.1.6 Peroxidases
Subcellular Localization
  • Cytoplasm, cytosol
  • Peroxisome matrix
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
peroxisome A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.

3 GO annotations of molecular function

Name Definition
catalase activity Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
metal ion binding Binding to a metal ion.

2 GO annotations of biological process

Name Definition
hydrogen peroxide catabolic process The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2).
response to oxidative stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDPYKYRSSS AYNAPFWTTN SGAPVYNNNN SLTVGSRGPI LLEDYHLVEK LANFDRERIP
70 80 90 100 110 120
ERVVHARGAS AKGFFEVTHD ITALTCADFL RAPGVQTPVI VRFSTVIHER GSPETLRDPR
130 140 150 160 170 180
GFAVKFYTRE GNFDLVGNNF PVFFIRDGMK FPDMVHSLKP NPKSHIQEDW RIMDFFSHHP
190 200 210 220 230 240
ESLHMFTFLL DDIGVPQDYR HMDGSGVNTY TLINKAGKAY YVKFHWKPTC GVKSLLEEEA
250 260 270 280 290 300
IKIGGANHSH ATQDLYDSIA AGNYPEWKLF IQTIDPDHED RLDFDPLDVT KTWPEDIFPL
310 320 330 340 350 360
QPVGRLVLNK NIDNFFAENE QLAFCPAIIV PGIYYSDDKL LQTRIFSYSD TQRHRLGPNY
370 380 390 400 410 420
LQLPANAPKC AHHNNHYDGF MNFMHRDEEI DYFPSRYDPA RHAEQYPIPP VRLSGKRDKC
430 440 450 460 470 480
VIEKENNFKQ PGERYRSFSP DRQERFINRV VGGLSDPRVT HEVRSIWVSY WSQADKSLGQ
490
KIASRLNVKP NY