P45727

PR
Gene name
PAL
Protein name
Phenylalanine ammonia-lyase
Names
Species
Persea americana (Avocado)
KEGG Pathway
EC number
4.3.1.24: Ammonia-lyases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-57 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P45727

Entry ID Method Resolution Chain Position Source
AF-P45727-F1 Predicted AlphaFoldDB

No variants for P45727

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P45727

No associated diseases with P45727

1 regional properties for P45727

Type Name Position InterPro Accession
active_site Phenylalanine/histidine ammonia-lyases, active site 101 - 117 IPR022313

Functions

Description
EC Number 4.3.1.24 Ammonia-lyases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
phenylalanine ammonia-lyase activity Catalysis of the reaction: L-phenylalanine = NH(4)(+) + trans-cinnamate.

2 GO annotations of biological process

Name Definition
cinnamic acid biosynthetic process The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid.
L-phenylalanine catabolic process The chemical reactions and pathways resulting in the breakdown of phenylalanine, 2-amino-3-phenylpropanoic acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MESMDKGTDS YGVTTGFGAT SHRRTKQGGA LHKELIRFLN AGIFGTNGES GHTLAPSATR
70 80 90 100 110 120
AAMLVRINTL LQGYSGIRFE ILEAITSLLN HSITPCLPLR GTITASGDLV PLSYIAGMLT
130 140 150 160 170 180
GRPNSKGDWP DGKEIDAGEA FRLAGIPSGF FELQPKEGLA LVNGTAVGSG LASMVLFEAN
190 200 210 220 230 240
VLSVLSEVIS AIFCEVMQGK PEFTDHLTHK LKHHPGQIEA AAIMEHILDG SSYMKVAKKL
250 260 270 280 290 300
HELDPLQKPK QDPYAALRTS PQWLGPQIEV IRNATLSIER EINSVNDNPL IDVSRNKALH
310 320 330 340 350 360
GRNFQGTPIG VSMDNTRLAI AAIGKLMFAQ FSELVNDFYN NGLPSNLSGG RNPSLDYGFK
370 380 390 400 410 420
GAEIAMAAYC SELQFLANPV TNHVQSAEQH NQDVNSLGLI SSRKTAEAVE ILKLMSSTFL
430 440 450 460 470 480
VGLCQAIDLR HLEENLKSTV KNTVSQVAKR VLTIGVNGEL HPSRFCEKDL IKVVDGEHLF
490 500 510 520 530 540
AYIDDPCSCT YPLMQKLRQV LVEHALINGE KEKDSSTSIF QKIGAFEEEL KTHLPKEVES
550 560 570 580 590 600
ARIELERGNS AIPNRIKECR SYPLYKFVRE ELKTSLLTGE KVRSPGEEFD KVFSAICQGK
610
VIDPLLECLR EWNGAPIPIC