Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P45675

Entry ID Method Resolution Chain Position Source
AF-P45675-F1 Predicted AlphaFoldDB

No variants for P45675

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P45675

No associated diseases with P45675

1 regional properties for P45675

Type Name Position InterPro Accession
conserved_site TATA-box binding protein, conserved site 143 - 192 IPR030491

Functions

Description
EC Number 2.7.13.3 Protein-histidine kinases
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein histidine kinase activity Catalysis of the reaction: ATP + protein L-histidine = ADP + protein phospho-L-histidine.

2 GO annotations of biological process

Name Definition
nitrogen fixation The process in which nitrogen is taken from its relatively inert molecular form (N2) in the atmosphere and converted into nitrogen compounds useful for other chemical processes, such as ammonia, nitrate and nitrogen dioxide.
phosphorelay signal transduction system A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSPTPPETVT PLWQQFLRWA ARVGLAKRLA FALSLAALVA GFATYTALTE SAPFGETNPR
70 80 90 100 110 120
TVTWLLTLDL ALLLLLGVLI ARRIVYLWIG RRRGLAGSQM HVRLVAVFSL LAVAPAIIMA
130 140 150 160 170 180
IFSTVFFYVG VQSWFSERVR TAVNESLAVA SAYLHEHQQN IRADALAMAN DLNQEAARLA
190 200 210 220 230 240
SDPERFEQVV ATQAMLRALS EAIVFNGTTG AIVARSGYTF ALEFDPIPDD KLATARRGEV
250 260 270 280 290 300
AMIVSENDDR VRALVRLDRF ADTYLYVGRM VEPRVLSHMA SAEGAVREFG ALESQRGSLQ
310 320 330 340 350 360
ITFTLIFLCV ALLLLLAAVW AGLIFATRLV RPISALIGAA DRVRAGDLTV RVTERPAEDD
370 380 390 400 410 420
LALLSRAFNR MTTEIESQRH ALLSANRLID SRRRFTETVL SGVSAGRDGL DAEGRITLSK
430 440 450 460 470 480
FSAARLLGVK DAESLIGMRL AELVPEMGGL LHEAPGRPGL VVQDQIKIRR DGTTPLTLLV
490 500 510 520 530 540
RISTEGRGSG MMRGYVVTFD EHHRTWSPAQ RKAAWARRRP IAASPTRVKN PLTPIQLSAE
550 560 570 580 590 600
PCAASTLKEI TSDTEVFTMC TDTIVRQVDD IRRMVDEFSA FARMPQPVMK PCNLNDLVRQ
610 620 630 640 650 660
AVFLQSSAHA GKIKFDMALP QGPLTVPCDS RQISQALTNL LQNAADAIEG RPPPAEGTEL
670 680 690 700 710 720
PPGHVAIRVE ADAERIAMII EDNGKGLPTE ERDRLTEPYV TTRAKGTGLG LAIVKKIMED
730 740 750 760 770
HGGVLTLEDR EGGGARVGLV IPQHIPPASG TAAGDAPGGV GTPAETGEEK RHAAHGA