Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P45512
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P45512-F1 | Predicted | AlphaFoldDB |
No variants for P45512
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P45512 | |||||
No associated diseases with P45512
7 regional properties for P45512
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | PAS domain | 203 - 303 | IPR000014 |
| domain | RNA polymerase sigma factor 54 interaction domain | 327 - 552 | IPR002078 |
| domain | DNA binding HTH domain, Fis-type | 590 - 628 | IPR002197 |
| domain | AAA+ ATPase domain | 347 - 488 | IPR003593 |
| domain | PAS fold | 204 - 306 | IPR013767 |
| binding_site | Sigma-54 interaction domain, ATP-binding site 1 | 351 - 364 | IPR025662 |
| binding_site | Sigma-54 interaction domain, ATP-binding site 2 | 410 - 425 | IPR025943 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| sequence-specific DNA binding | Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| glycerol metabolic process | The chemical reactions and pathways involving glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids. |
| nitrogen compound metabolic process | The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen. |
| regulation of DNA-templated transcription | Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTTHTQDIGK | EVSSVIAQSW | HRCSKFMQRE | TWQAPHQAQG | LTFESICRRK | TALLTIAQAA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LEDAWEFMDG | RPCALLILDE | SACILSRCGD | PQTVEQLAEL | GFRDGSYCAE | SIIGSCALSL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ATMPGQPTKT | SGDQHFKQAL | HPWSFCSTPV | FDNHGRLFGS | ISLCCLVEHE | CVSDLSLTLA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| IAREVGNSLL | TDSLLAESNR | HLNQMYGLLE | SMDDGVMAWN | EQGVLQFLNA | RAALLLHLDA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| QASQGKNIND | LLNLPMLLRR | AIKHARGLNH | VEVTFESQHQ | FVDAVITLKP | IVEEQGNSFI |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LLLHPVEQMR | QLMTSQLGKV | SHTFEQMSTD | DPETRRLIHF | GRQAARGSFP | ILLCGEEGVG |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KELLSQAIHN | ESERASGPYI | AVNCQLYANS | VLGQDFMGSA | PTDDENGRLS | RLELANGGTL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| FLEKIEYLAP | ELQSALLQVI | KQGVLTRLDA | RRLIPVDVKV | IATTTVDLAN | LVEQNRFSRQ |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LYYALHSFEI | VIPPLRARRN | SIPSLIYTRL | NSLKKRFSSS | LKIDDDALAQ | LVAYSWPGND |
| 550 | 560 | 570 | 580 | 590 | 600 |
| FELNSIIENI | AISSDNGHIR | LSNLPDYLFA | ERPGLETASS | LLPASLTFTA | IEKEAIIHAA |
| 610 | 620 | 630 | 640 | ||
| RVTSGRVQEM | SQLLNIGRTT | LWRKMKQYDI | DASQFKRKHL | E |