P45285

PR
Gene name
sapA (HI_1638)
Protein name
Peptide transport periplasmic protein SapA
Names
Species
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
KEGG Pathway
hin:HI_1638
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-57 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P45285

Entry ID Method Resolution Chain Position Source
AF-P45285-F1 Predicted AlphaFoldDB

No variants for P45285

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P45285

No associated diseases with P45285

2 regional properties for P45285

Type Name Position InterPro Accession
domain Solute-binding protein family 5 domain 79 - 480 IPR000914
conserved_site Solute-binding protein family 5, conserved site 84 - 106 IPR023765

Functions

Description
EC Number
Subcellular Localization
  • Periplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
ATP-binding cassette (ABC) transporter complex A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter.
outer membrane-bounded periplasmic space The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall.

1 GO annotations of molecular function

Name Definition
peptide transmembrane transporter activity Enables the transfer of a peptide from one side of a membrane to the other.

2 GO annotations of biological process

Name Definition
peptide transport The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLRLNLRFLS FLLCIIQSVE LQAAPSVPTF LTENGLTYCT HASGFSFNPQ TADAGTSMNV
70 80 90 100 110 120
VTEQIYNKLF DIKNHSATLT PMLAQSYSIS ADGKEILLNL RHGVKFHQTP WFTPTRDFNA
130 140 150 160 170 180
EDVVFSINRV LGGHNTYLPT LAETNVTYSN PQYRVFHEQA RKVRFPYFDS IKLNEKIKSV
190 200 210 220 230 240
TALSPYQVKI ELFAPDSSIL SHLASQYAII FSQEYAYQLS ADDNLAQLDT HPVGTGPYQV
250 260 270 280 290 300
KDYVYNQYVR LVRNENYWKK EAKIEHIIVD LSTDRSGRLV KFFNNECQIA SYPEVSQIGL
310 320 330 340 350 360
LKNDDKHYYM QSTDGMNLAY LAFNFDKPLM RDHEIRAAIS QSLNRARIIH SIYHNTATVA
370 380 390 400 410 420
NNIIPEVSWA SSVNTPEFEF DYNPKIAKNK LADKNLLLNL WVINEEQVYN PAPFKIAEMI
430 440 450 460 470 480
KWDLAQAGVK VKVRAVTRPF LTAQLRNQSE NYDLILSGWL AGNLDPDGFM RPILSCGTKN
490 500 510 520 530 540
ELTNLSNWCN EEFDQFMDRA ITTSHLSSRA KAYNEAQELV LRELPIIPIA NVKRILVANS
550 560
RVKGVKMTPF GSLDFSTLYF IQEKY