P45239
Gene name |
lpxL |
Protein name |
Lipid A biosynthesis lauroyltransferase |
Names |
Kdo(2)-lipid IV(A) lauroyltransferase |
Species |
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) |
KEGG Pathway |
hin:HI_1527 |
EC number |
2.3.1.241: Transferring groups other than amino-acyl groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P45239
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P45239-F1 | Predicted | AlphaFoldDB |
No variants for P45239
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P45239 | |||||
No associated diseases with P45239
No regional properties for P45239
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P45239 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.3.1.241 | Transferring groups other than amino-acyl groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of plasma membrane | The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| lauroyltransferase activity | Catalysis of the transfer of a lauroyl (dodecanoyl) group from one compound to another. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| Kdo2-lipid A biosynthetic process | The chemical reactions and pathways resulting in the formation of Kdo2-lipid A, a lipopolysaccharide (LPS) component. |
| lipid A biosynthetic process | The chemical reactions and pathways resulting in the formation of lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common. |
| lipopolysaccharide biosynthetic process | The chemical reactions and pathways resulting in the formation of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKNEKLPQFQ | PHFLAPKYWL | FWLGVAIWRS | ILCLPYPILR | HIGHGFGWLF | SHLKVGERRA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AIARRNLELC | FPDMPENERE | VILQENLRSV | GMAIIETGMA | WFWSDSRIKK | WSKVEGLHYL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KENQKDGIVL | VGVHFLTLEL | GARIIGLHHP | GIGVYRPNDN | PLLDWLQTQG | RLRSNKDMLD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RKDLRGMIKA | LRHEETIWYA | PDHDYGRKNA | VFVPFFAVPD | TCTTTGSYYL | LKSSQNSKVI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| PFAPLRNKDG | SGYTVSISAP | VDFTDLQDET | AIAARMNQIV | EKEIMKDITI | YMWLHRRFKT |
| 310 | |||||
| RPDEKTPSLY | D |