Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

6 structures for P45206

Entry ID Method Resolution Chain Position Source
1OU8 X-ray 160 A A/B 1-111 PDB
1OU9 X-ray 180 A A/B/C 1-129 PDB
1OUL X-ray 220 A A/B 1-129 PDB
1TWB X-ray 190 A A/B 1-110 PDB
1ZSZ X-ray 200 A PDB
AF-P45206-F1 Predicted AlphaFoldDB

No variants for P45206

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P45206

No associated diseases with P45206

No regional properties for P45206

Type Name Position InterPro Accession
No domain, repeats, and functional sites for P45206

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
ribosome An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
positive regulation of protein catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEYKSSPKRP YLLRAYYDWL VDNSFTPYLV VDATYLGVNV PVEYVKDGQI VLNLSASATG
70 80 90 100 110 120
NLQLTNDFIQ FNARFKGVSR ELYIPMGAAL AIYARENGDG VMFEPEEIYD ELNIEPDTEQ
130 140
PTGFYEAVDK PKKREEKKKT KSVSHLRIVD