P45105

PR
Gene name
cysB (HI_1200)
Protein name
HTH-type transcriptional regulator CysB
Names
Cys regulon transcriptional activator
Species
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
KEGG Pathway
hin:HI_1200
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

269-323 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P45105

Entry ID Method Resolution Chain Position Source
AF-P45105-F1 Predicted AlphaFoldDB

No variants for P45105

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P45105

No associated diseases with P45105

3 regional properties for P45105

Type Name Position InterPro Accession
domain Transcription regulator HTH, LysR 1 - 64 IPR000847
domain LysR, substrate-binding 90 - 291 IPR005119
domain HTH-type transcriptional regulator CysB, PBP2 domain 95 - 290 IPR037423

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
transcription cis-regulatory region binding Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.

2 GO annotations of biological process

Name Definition
cysteine biosynthetic process The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid.
regulation of DNA-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKMHQLRYIV EIVNQNLNVT EAANALYTSQ PGISKQVRLL EDELGLEIFE RHGKHIKSIT
70 80 90 100 110 120
PAGKKIISIA RELLVKAQGI RAVADEYTRP NHGVLRIATT NTQARYMLPS VIERFSKKYP
130 140 150 160 170 180
DVSLHIHQGS PTQIHDALMS GEVDLAITTE APYLFDDLVQ IPCYWWNRAV IVSPEHPLAK
190 200 210 220 230 240
VKELTIEELG KYPLVTYTFG FTGVSDLDYA FNSAGILPNI VFTATDADVI KTYVRLGLGV
250 260 270 280 290 300
GIMASMAHTA LDTDLVLIDA SHLFRPSMTN IAFKHSTFLR NYMYDFMEYF SPHLTRSVVE
310 320
KAERLRDNNS VKKLFEGIEL ETK