P44920

PR
Gene name
coaE
Protein name
Dephospho-CoA kinase
Names
Dephosphocoenzyme A kinase
Species
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
KEGG Pathway
hin:HI_0890
EC number
2.7.1.24: Phosphotransferases with an alcohol group as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

105-192 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

2 structures for P44920

Entry ID Method Resolution Chain Position Source
1JJV X-ray 200 A A 1-206 PDB
AF-P44920-F1 Predicted AlphaFoldDB

No variants for P44920

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P44920

No associated diseases with P44920

6 regional properties for P44920

Type Name Position InterPro Accession
domain Tetrapyrrole methylase 6 - 218 IPR000878-1
domain Tetrapyrrole methylase 249 - 456 IPR000878-2
conserved_site Uroporphiryn-III C-methyltransferase, conserved site 10 - 24 IPR003043-1
conserved_site Uroporphiryn-III C-methyltransferase, conserved site 103 - 135 IPR003043-2
domain Precorrin-3B C17-methyltransferase domain 249 - 492 IPR006363
domain Precorrin-2 C(20)-methyltransferase domain 5 - 236 IPR006364

Functions

Description
EC Number 2.7.1.24 Phosphotransferases with an alcohol group as acceptor
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
dephospho-CoA kinase activity Catalysis of the reaction: 3'-dephospho-CoA + ATP = ADP + CoA + 2 H(+).

2 GO annotations of biological process

Name Definition
coenzyme A biosynthetic process The chemical reactions and pathways resulting in the formation of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTYIVGLTGG IGSGKTTIAN LFTDLGVPLV DADVVAREVV AKDSPLLSKI VEHFGAQILT
70 80 90 100 110 120
EQGELNRAAL RERVFNHDED KLWLNNLLHP AIRERMKQKL AEQTAPYTLF VVPLLIENKL
130 140 150 160 170 180
TALCDRILVV DVSPQTQLAR SAQRDNNNFE QIQRIMNSQV SQQERLKWAD DVINNDAELA
190 200
QNLPHLQQKV LELHQFYLQQ AENKNA