P44836

PR
Gene name
HI_0712
Protein name
Probable hemoglobin and hemoglobin-haptoglobin-binding protein 3
Names
Species
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
KEGG Pathway
hin:HI_0712
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-162 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P44836

Entry ID Method Resolution Chain Position Source
AF-P44836-F1 Predicted AlphaFoldDB

No variants for P44836

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P44836

No associated diseases with P44836

4 regional properties for P44836

Type Name Position InterPro Accession
domain TonB-dependent receptor-like, beta-barrel 542 - 1082 IPR000531
repeat PT repeat 25 - 84 IPR006970
conserved_site TonB-dependent receptor, conserved site 1067 - 1084 IPR010917
domain TonB-dependent receptor, plug domain 104 - 213 IPR012910

Functions

Description
EC Number
Subcellular Localization
  • Cell outer membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
intrinsic component of cell outer membrane The component of the cell outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.

1 GO annotations of molecular function

Name Definition
siderophore uptake transmembrane transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: siderophore-iron(ferrioxamine)(out) + H+(out) = siderophore-iron(ferrioxamine)(in) + H+(in).

2 GO annotations of biological process

Name Definition
organic substance transport The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon.
siderophore transmembrane transport The directed movement of siderophores, low molecular weight Fe(III)-chelating substances, from one side of a membrane to the other, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTNFKFSLLA CSIAFALNAS TVYAAQPTNQ PTNQPTNQPT NQPTNQPTNQ PTNQPTNQPT
70 80 90 100 110 120
NQPTNQPTNQ PTNQNSNVSE QLEQINVSGS SENINIKEKK VGETQISAKK LAKQQASDSR
130 140 150 160 170 180
DLVRYETGIT VVETGRTGAS GYAVRGVDEN RVGIMVDGLR QAETLSSQGF KELFEGYGNF
190 200 210 220 230 240
NNTRNSIEIE NVKTATITKG ADSLKSGSGA LGGSVIFETK DARDYLIDKD YYLSYKRGYQ
250 260 270 280 290 300
TMNNQNLKTL TLAGRSKKFD ILIIDTTRDG HEIENYDYKI YPNKQADLRA VGPTREKADP
310 320 330 340 350 360
YQITRQSTLI KLGFQPNENH RLSVALDDST LETKGIDLSY ALRPYSTAGN EKYGERIIND
370 380 390 400 410 420
QSKRKNIQFS YENFSQTPFW DHIKLSYSSQ KITNKARSDE YCHQSTCNGV SNPQGLHLVE
430 440 450 460 470 480
EGGVYKIVDK NGDKLTYNKN AGWYGQFQNK NGENVDNDID STGGSLDSVL IDCERLNCKN
490 500 510 520 530 540
KFQVFVEKDE EGKDKYEYEE RDIIVETLPN GKKYGKITLK KGKTPLWDDV YQEESARFLF
550 560 570 580 590 600
PKSYGYSTDF VNDRDLNTNT QQIKLDLDKE FSLWHTQHSL KYGGFYEKTL KSMVNHQYNT
610 620 630 640 650 660
VANVQWWAGN FFCNKLENGK RTPAPDYSHR CSLMNTDKGK ETYLIPVTTK NNVLYFGDNV
670 680 690 700 710 720
QLTSWLGLDL NYRYDHVKYL PSYDEKIPVP NGLITGLFKK FGPKDYVYGS KYSKPADYTD
730 740 750 760 770 780
CTYNSDCYKK NFKDNLALLL RKTDYKHHSY NLGLNLDPTD WLRVQLKYAN GFRAPTSDEI
790 800 810 820 830 840
YMTFKHPQFS IQPNTDLKAE TSKTKEVAFT FYKNSSYITL NAFQNDYRNF IDLVEVGPRP
850 860 870 880 890 900
IEEGSTIAYP FHQNQNRDRA RVRGIEIASR LEMGDLFEKL QGFHLGYKFT YQKGRIKDNG
910 920 930 940 950 960
LNPKYKEFLE LNKDKHPEYE AIARKPQPMN ALQPTTSVYN IGYDAPSQKW GVDMYITNVA
970 980 990 1000 1010 1020
AKKAKDSFNS QWTSMVKRKE KIYGNEKDAE ASTANGKEVK DSRGLWRNNR YTVIDTIAYW
1030 1040 1050 1060 1070 1080
KPIKNLTFTA GVYNLTNKKY LTWDSARSIR HLGTINRVET ATGKGLNRFY APGRNYRMSV
QFEF