P44770

PR
Gene name
arcB (HI_0596)
Protein name
Ornithine carbamoyltransferase, catabolic
Names
OTCase
Species
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
KEGG Pathway
hin:HI_0596
EC number
2.1.3.3: Carboxy- and carbamoyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

48-117 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P44770

Entry ID Method Resolution Chain Position Source
AF-P44770-F1 Predicted AlphaFoldDB

No variants for P44770

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P44770

No associated diseases with P44770

2 regional properties for P44770

Type Name Position InterPro Accession
domain Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain 156 - 331 IPR006131
domain Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding 8 - 148 IPR006132

Functions

Description
EC Number 2.1.3.3 Carboxy- and carbamoyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
amino acid binding Binding to an amino acid, organic acids containing one or more amino substituents.
ornithine carbamoyltransferase activity Catalysis of the reaction: carbamoyl phosphate + L-ornithine = phosphate + L-citrulline.

4 GO annotations of biological process

Name Definition
arginine biosynthetic process via ornithine The chemical reactions and pathways resulting in the formation of arginine (2-amino-5-guanidinopentanoic acid) via the intermediate compound ornithine.
arginine catabolic process to ornithine The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including ornithine.
arginine deiminase pathway The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including ornithine and CO2, using the enzyme arginine deiminase.
citrulline biosynthetic process The chemical reactions and pathways resulting in the formation of citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAFNMKNRHL LSLVHHTERE IKYLLDLSRD LKRAKYAGTE QQKLKGKNIA LIFEKTSTRT
70 80 90 100 110 120
RCAFEVAAYD QGAQVTYIDP NSSQIGHKES MKDTARVLGR MYDGIEYRGF KQSIVQELAD
130 140 150 160 170 180
YAGVPVFNGL TDEFHPTQML ADVLTMIEHC DKPLSEISYV YIGDARNNMG NSLLLIGAKL
190 200 210 220 230 240
GMDVRICGPK ALLPEANLVE MCEKFAKESG ARITVTEDID KAVKGVDFIH TDVWVSMGEP
250 260 270 280 290 300
LETWGERIKL LLPYQVTPEL MKRTGNPKVK FMHCLPAFHN SETKVGRQIA EKYPELANGI
310 320 330
EVTEEVFESP MNIAFEQAEN RMHTIKAVMV ASLA