P44740

PR
Gene name
trmO
Protein name
tRNA (adenine(37)-N6)-methyltransferase
Names
tRNA (m6t6A37) methyltransferase, tRNA methyltransferase O
Species
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
KEGG Pathway
hin:HI_0510
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-232 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

2 structures for P44740

Entry ID Method Resolution Chain Position Source
1XQB X-ray 285 A A/B 1-239 PDB
AF-P44740-F1 Predicted AlphaFoldDB

No variants for P44740

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P44740

No associated diseases with P44740

1 regional properties for P44740

Type Name Position InterPro Accession
domain tRNA/rRNA methyltransferase, SpoU type 5 - 154 IPR001537

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
tRNA binding Binding to a transfer RNA.
tRNA m6t6A37 methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA containing N6-threonylcarbamoyladenosine = S-adenosyl-L-homocysteine + tRNA containing N6-methylthreonylcarbamoyladenosine.

1 GO annotations of biological process

Name Definition
tRNA methylation The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNDLTLSPIA IIHTPYKEKF SVPRQPNLVE DGVGIVELLP PYNSPEAVRG LEQFSHLWLI
70 80 90 100 110 120
FQFDQIQQGK WQPTVRPPRL GGNQRVGVFA SRATHRPNPL GLSKVELRQV ECINGNIFLH
130 140 150 160 170 180
LGAVDLVDGT PIFDIKPYIA YADSEPNAQS SFAQEKLPVK LTVEFTEQAK SAVKKREEKR
190 200 210 220 230
PHLSRFIRQV LEQDPRPAYQ QGKPSDRIYG MSLYEFNVKW RIKAGTVNCV EVIEIEKDK