P44701
Gene name |
srmB |
Protein name |
ATP-dependent RNA helicase SrmB |
Names |
|
Species |
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) |
KEGG Pathway |
hin:HI_0422 |
EC number |
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P44701
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P44701-F1 | Predicted | AlphaFoldDB |
No variants for P44701
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P44701 | |||||
No associated diseases with P44701
5 regional properties for P44701
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | ATP-dependent RNA helicase DEAD-box, conserved site | 155 - 163 | IPR000629 |
| domain | Helicase, C-terminal | 235 - 387 | IPR001650 |
| domain | DEAD/DEAH box helicase domain | 28 - 192 | IPR011545 |
| domain | Helicase superfamily 1/2, ATP-binding domain | 23 - 225 | IPR014001 |
| domain | RNA helicase, DEAD-box type, Q motif | 4 - 32 | IPR014014 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.6.4.13 | Acting on ATP; involved in cellular and subcellular movement |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
| nucleic acid binding | Binding to a nucleic acid. |
| RNA helicase activity | Unwinding of an RNA helix, driven by ATP hydrolysis. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| ribosomal large subunit assembly | The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNLSQFEQFD | LSPELLKALE | KKGYSRPTAI | QMEAIPAAME | ESDVLGSAPT | GTGKTAAFLL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PALQHLLDYP | RRKPGPPRIL | VLTPTRELAM | QVAEQAEELA | QFTHLNIATI | TGGVAYQNHG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DVFNTNQDLV | VATPGRLLQY | IKEENFDCRS | VEMLIFDEAD | RMLQMGFGQD | AEKIAAETRW |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RKQTLLFSAT | LEGELLVDFA | ERLLNDPVKV | DAEPSRRERK | KINQWYYHAD | SNEHKIKLLA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| RFIETEEVTR | GIVFIRRRED | ARELSETLRK | RGIRSAYLEG | EMAQTQRNNA | IDKLKSGIVT |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VLVATDVAAR | GIDIDDVSHV | MNFDLPYSAD | TYLHRIGRTA | RAGKKGTAVS | FVEAHDYKLL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| GKIKRYTEEI | LKARILAGLE | PRTKPPKDGE | VKSVSKKQKA | RIKEKREEKK | KTEAKKKVKL |
| 430 | |||||
| RHKDTKNIGK | RRKPSNSNV |