P44619
Gene name |
rho |
Protein name |
Transcription termination factor Rho |
Names |
ATP-dependent helicase Rho |
Species |
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) |
KEGG Pathway |
hin:HI_0295 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P44619
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P44619-F1 | Predicted | AlphaFoldDB |
No variants for P44619
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P44619 | |||||
No associated diseases with P44619
6 regional properties for P44619
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain | 161 - 364 | IPR000194 |
| domain | AAA+ ATPase domain | 171 - 356 | IPR003593 |
| domain | Rho termination factor, N-terminal | 5 - 48 | IPR011112 |
| domain | Rho termination factor, RNA-binding domain | 49 - 126 | IPR011113 |
| domain | Cold shock domain | 53 - 119 | IPR011129 |
| domain | Transcription termination factor Rho, ATP binding domain | 157 - 405 | IPR041703 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
5 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP-dependent activity, acting on RNA | Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of RNA, and it drives another reaction. |
| helicase activity | Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix. |
| hydrolase activity | Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA-templated transcription termination | The completion of transcription: the RNA polymerase pauses, the RNA-DNA hybrid dissociates, followed by the release of the RNA polymerase from its DNA template. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MHLTELKNTP | VSDLVKLGEE | QMGLENLARL | RKQDIVFAIL | KQHAKSGEDI | FGGGVLEILP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DGFGFLRSAD | SSYLAGPDDI | YVSPSQIRRF | NLQTGDKIEG | KIRPPKEGER | YFALLKVDQV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NDDKPEVSRS | KILFENLTPL | HANSRLRMER | GNGSTEDLTA | RILDLASPIG | KGQRGLIVAP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PKAGKTMLLQ | NIAQSITHNY | PDVELIVLLI | DERPEEVTEM | QRSVKGEVIA | STFDEPATRH |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VQVAEMVIEK | AKRSVEHKKD | VVILLDSITR | LARAYNTVTP | ASGKILSGGV | DANALHRPKR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| FFGAARNVEE | GGSLTIIATA | LVDTGSKMDE | VIFEEFKGTG | NMELHLSRKI | AERRVFPAID |
| 370 | 380 | 390 | 400 | 410 | |
| FKRSGTRKED | LLTTADELQK | MWILRKILNP | MDEVDAMEFL | IDKLMMAKTN | EEFFEVMKRS |