P44573
Gene name |
prlC (HI_0214) |
Protein name |
Oligopeptidase A |
Names |
|
Species |
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) |
KEGG Pathway |
hin:HI_0214 |
EC number |
3.4.24.70: Metalloendopeptidases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P44573
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P44573-F1 | Predicted | AlphaFoldDB |
No variants for P44573
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P44573 | |||||
No associated diseases with P44573
Functions
| Description | ||
|---|---|---|
| EC Number | 3.4.24.70 | Metalloendopeptidases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| metalloendopeptidase activity | Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| peptide metabolic process | The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. |
| proteolysis | The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSMSNPLLNI | QGLPPFSQIK | PEHIRPAVEK | LIQDCRNTIE | QVLKQPHFTW | ENFILPLTET |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NDRLNRAWSP | VSHLNSVKNS | TELREAYQTC | LPLLSEYSTW | VGQHKGLYNA | YLALKNSAEF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ADYSIAQKKA | IENSLRDFEL | SGIGLSEEKQ | QRYGEIVARL | SELNSQFSNN | VLDATMGWEK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LIENEAELAG | LPESALQAAQ | QSAESKGLKG | YRFTLEIPSY | LPVMTYCENR | ALREEMYRAY |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ATRASEQGPN | AGKWDNSKVM | EEILTLRVEL | AKLLGFNTYT | ELSLATKMAE | NPQQVLDFLD |
| 310 | 320 | 330 | 340 | 350 | 360 |
| HLAERAKPQG | EKELQELKGY | CEKEFGVTEL | APWDIGFYSE | KQKQHLYAIN | DEELRPYFPE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| NRVISGLFEL | IKRIFNIRAV | ERKGVDTWHK | DVRFFDLIDE | NDQLRGSFYL | DLYAREHKRG |
| 430 | 440 | 450 | 460 | 470 | 480 |
| GAWMDDCIGR | KRKLDGSIET | PVAYLTCNFN | APIGNKPALF | THNEVTTLFH | EFGHGIHHML |
| 490 | 500 | 510 | 520 | 530 | 540 |
| TQIDVSDVAG | INGVPWDAVE | LPSQFMENWC | WEEEALAFIS | GHYETGEPLP | KEKLTQLLKA |
| 550 | 560 | 570 | 580 | 590 | 600 |
| KNFQAAMFIL | RQLEFGIFDF | RLHHTFDAEK | TNQILDTLKS | VKSQVAVIKG | VDWARAPHSF |
| 610 | 620 | 630 | 640 | 650 | 660 |
| SHIFAGGYAA | GYYSYLWAEV | LSADAYSRFE | EEGIFNPITG | KSFLDEILTR | GGSEEPMELF |
| 670 | 680 | ||||
| KRFRGREPQL | DALLRHKGIM | N |