P44516

PR
Gene name
htpG
Protein name
Chaperone protein HtpG
Names
Heat shock protein HtpG, High temperature protein G
Species
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
KEGG Pathway
hin:HI_0104
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

460-594 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P44516

Entry ID Method Resolution Chain Position Source
AF-P44516-F1 Predicted AlphaFoldDB

No variants for P44516

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P44516

No associated diseases with P44516

3 regional properties for P44516

Type Name Position InterPro Accession
domain Histidine kinase/HSP90-like ATPase 28 - 185 IPR003594
conserved_site Heat shock protein Hsp90, conserved site 26 - 35 IPR019805
domain Heat shock protein Hsp90, N-terminal 6 - 209 IPR020575

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
ATP-dependent protein folding chaperone Binding to a protein or a protein-containing complex to assist the protein folding process, driven by ATP hydrolysis.
unfolded protein binding Binding to an unfolded protein.

3 GO annotations of biological process

Name Definition
cellular response to DNA damage stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
protein folding The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
response to heat Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSQNQETRGF QSEVKQLLQL MIHSLYSNKE IFLRELISNA SDAADKLRFK ALSNPALYEG
70 80 90 100 110 120
DGDLRVRVSF DADKGTITIS DNGIGMTREQ VIDHLGTIAK SGTKEFLTAL GQDQAKNSQL
130 140 150 160 170 180
IGQFGVGFYS AFIVADKVTV KTRAAGEEAD KAVLWESAGE GEYSVADIEK KSRGTDVILH
190 200 210 220 230 240
LREDEKEFLN EWRLREIIGK YSDHIGLPVE MLTKEYDDEG KECGEKWEKI NKSDALWTRS
250 260 270 280 290 300
KNDVSDEEYK AFYKHLSHDF VDPVTWAHNK VEGNQAYTSL LYVPAKAPWD LFNREHKHGL
310 320 330 340 350 360
KLYVQRVFIM DDAEQFIPNY LRFMRGLIDS NDLPLNVSRE ILQDNKITAA LRKALTKRSL
370 380 390 400 410 420
QMLEKLAKDD AEKYLQFWKE FGLVLKEGPA EDFANKETVA KLLRFASTHN DGSEQTVSLE
430 440 450 460 470 480
DYILRMKEGQ KAIYYITADS YVAAKNSPHL ELFNKKGIEV LLLSDRIDEW MLSYLTEFDG
490 500 510 520 530 540
KQLQSITKAD LDLGDLADKE SETQKQQDEA FGSFIERVKN LLGERVKTVR LTHNLTDTPA
550 560 570 580 590 600
VVSTDNDQMT TQMAKLFAAA GQPVPEVKYT FELNPEHHLV KKVADIADET EFADWVELLL
610 620
EQAMLAERGS LENPAAFIKR INKLLG