Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P44012

Entry ID Method Resolution Chain Position Source
AF-P44012-F1 Predicted AlphaFoldDB

No variants for P44012

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P44012

No associated diseases with P44012

2 regional properties for P44012

Type Name Position InterPro Accession
active_site Ribonuclease T2, His active site 1 145 - 152 IPR018188
active_site Ribonuclease T2, His active site 2 191 - 202 IPR033130

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
ribonuclease T2 activity Catalysis of the two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates.
RNA binding Binding to an RNA molecule or a portion thereof.

1 GO annotations of biological process

Name Definition
RNA catabolic process The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKKLTSILSL IVLVILAIWQ YFTDTTKTKH QSSSPVIEQT KQTKVSEPKF EPKFEPKFEP
70 80 90 100 110 120
KFEPQFETKR TDIEKSAVKN PDVFANYDVI MRNDHIGQNA KAPVDYYMLA LSWSPGFCDI
130 140 150 160 170 180
QREKYGDQLP YSSQYQCGNN RTFGWVVHGL WPQNANARAV SDHPRFCKGD LPALPKGLLA
190 200 210 220 230 240
QYLAISPGEK LLQGEWEKHG SCAFDSAQQY FAKEQELFNA LKLPNQKLSR DELFGWMKQH
250 260 270
NPQLKNAYLR ASRNELFICY DKKWQVMNCQ SK