P43919

PR
Gene name
glnD
Protein name
Bifunctional uridylyltransferase/uridylyl-removing enzyme
Names
UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein
Species
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
KEGG Pathway
hin:HI_1719
EC number
2.7.7.59: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

584-654 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P43919

Entry ID Method Resolution Chain Position Source
AF-P43919-F1 Predicted AlphaFoldDB

No variants for P43919

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P43919

No associated diseases with P43919

6 regional properties for P43919

Type Name Position InterPro Accession
domain ACT domain 706 - 789 IPR002912-1
domain ACT domain 815 - 899 IPR002912-2
domain Polymerase, nucleotidyl transferase domain 73 - 110 IPR002934
domain HD/PDEase domain 457 - 611 IPR003607
domain HD domain 461 - 590 IPR006674
domain PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase 185 - 324 IPR013546

Functions

Description
EC Number 2.7.7.59 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
[protein-PII] uridylyltransferase activity Catalysis of the reaction: UTP + (protein-PII) = diphosphate + uridylyl-(protein-PII).
phosphoric diester hydrolase activity Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group.

2 GO annotations of biological process

Name Definition
nitrogen compound metabolic process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen.
regulation of nitrogen utilization Any process that modulates the frequency, rate or extent of nitrogen utilization.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLFSPTLSSL LTPSAVKIER ENLKQFELEN FSCYSIFELI ENRCDFYDAL LIQLWQEIGL
70 80 90 100 110 120
SEQQGISLIA VGGYGRREMF PLSDLDFLIL VEQTPSHEIE EKITQFIQFL WDCGFEVGNS
130 140 150 160 170 180
VRTLEQCELE GKQDITIATN LLEARFLTGN RPHFDVLNEL VKRADFWSKE DFFNAKVQEQ
190 200 210 220 230 240
IERYQRYHNT AYNLEPDIKF SPGGLRDLHL LYWVALRHSG ALTLEAILQS GFIYPQEYQQ
250 260 270 280 290 300
LQESRAFLFK VRFALHLILK RYDNRLLFDR QIKVSELLGF RGEGNPAVEK MMKCFFQALH
310 320 330 340 350 360
RISLISNLLI QHYRENVLSS NQDTVIDQLD DDFQLINQSL CLRNSFVFQE KPARILDLFF
370 380 390 400 410 420
YLTQYEHVNI HSDTLRQLQI SLEQLSQKLC EIPAAREKFL RLFNQSNAIK RAFMPMHQYG
430 440 450 460 470 480
VLTAYLPQWQ AIEGLMQFDL FHIYTVDEHT LRVMLKLESF LPKGSAQEHP IAHRIFSQLS
490 500 510 520 530 540
DRTLLYIAAL FHDIAKGRGG DHAELGAEDV ADFAQLHGLD RREIDTLAWL VQSHLLMSIT
550 560 570 580 590 600
AQRRDIHDPE VVMNFAEAMQ NQVRLDYLTC LTVADICATN GNLWNSWKRS LFASLYEFTE
610 620 630 640 650 660
QQFSQGMKEL LDYSEKSAEN RKLAQQILTQ DYSDITSISI EKLWTRCPED YFVRNTPKQI
670 680 690 700 710 720
AWHTSLLVDF VEALLVKISN RFSLGGTEVF IYCQDQPHLF NKVVSTIGAK KFSIHDAQII
730 740 750 760 770 780
TTQDGYVFDS FIITELNGEL VEFDRRRELE QALTVALQSE KLPALSIVPN RQLQHFTVQT
790 800 810 820 830 840
DVRFLQENKK EHTEMELVAL DKAGLLAQVS QIFTELNLNL LNAKITTVGE KAEDFFILTN
850 860
QFGQALAREE RERLNSVIIQ QIR