P43915

PR
Gene name
nusA
Protein name
Transcription termination/antitermination protein NusA
Names
Species
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
KEGG Pathway
hin:HI_1283
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

200-272 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P43915

Entry ID Method Resolution Chain Position Source
AF-P43915-F1 Predicted AlphaFoldDB

No variants for P43915

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P43915

No associated diseases with P43915

9 regional properties for P43915

Type Name Position InterPro Accession
domain S1 domain 133 - 200 IPR003029
domain K Homology domain 230 - 293 IPR004087-1
domain K Homology domain 301 - 379 IPR004087-2
domain Transcription termination factor NusA 5 - 342 IPR010213
repeat Transcription termination factor NusA, C-terminal duplication 365 - 414 IPR010214-1
repeat Transcription termination factor NusA, C-terminal duplication 441 - 490 IPR010214-2
domain Transcription factor NusA, N-terminal 4 - 123 IPR013735
domain RNA-binding domain, S1 133 - 200 IPR022967
domain KH domain, NusA-like 230 - 297 IPR025249

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

3 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
nucleotide binding Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.
RNA binding Binding to an RNA molecule or a portion thereof.

2 GO annotations of biological process

Name Definition
DNA-templated transcription termination The completion of transcription: the RNA polymerase pauses, the RNA-DNA hybrid dissociates, followed by the release of the RNA polymerase from its DNA template.
transcription antitermination Regulation of transcription by a mechanism that allows RNA polymerase to continue transcription beyond termination site(s).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSKEILLAAE AVSNEKLLPR EKIFEALESA IAISTKKKFE YETDIRVSIN PKTGEFDTFR
70 80 90 100 110 120
RWLVVDEVKV PTKEITLEAA QFDDPNLQLG EYVEDQIESI AFDRIAMQTA RQVISTKIRE
130 140 150 160 170 180
AERAKVVEQF REEEGKIVTG TVKKVSRDSI ILDLGNKAEA MIAREDMLPR ENFRPGDRVR
190 200 210 220 230 240
GVLYKVNPEG KTAQLFVTRS KPEMLIELFR IEVPEIGEEM IEIRGAARDA GSRAKIAVKS
250 260 270 280 290 300
NDKRIDPVGA CVGMRGARVQ VITNELGGER VDIVLWDDNP AQFVINAMAP ADVSSIIVDE
310 320 330 340 350 360
DNHSMDIAVE ADNLAQAIGR NGQNVRLATQ LTGWTLNVMT TDELNAKHQA EDNKVLNLFI
370 380 390 400 410 420
NALELDEEFA QILVEEGFTS LEEIAYVPMN ELTAIDGLED EDLVEELQTR AKNAITAAAV
430 440 450 460 470 480
AEEEALKKAN VEDRLLNLEG MNRHVAIKLA EKQITTLEEL AEQGVDDLTD IEELTAEQAA
490
DLIMAARNIC WFGEE